Results 151 to 160 of about 138,356 (258)

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

Predicting induction chemotherapy response based on tumor-stroma ratio and pretreatment synthetic MRI in nasopharyngeal carcinoma. [PDF]

open access: yesEur Radiol Exp
Ren H   +21 more
europepmc   +1 more source

Pyridoxal Reprograms Peroxisomal Hydrogen Peroxide Metabolism to Induce Lethal Oxidative Stress in Ovarian Cancer

open access: yesiMetaMed, EarlyView.
Pyridoxal (PL) exhibits the strongest anti‐tumor activity within the vitamin B6 family, demonstrating significant ovarian cancer cell‐killing efficacy in vivo, in vitro, and in patient‐derived organoid (PDO) models. The anti‐tumor mechanism involves PL inducing a shift in peroxisome dynamics towards fission, promoting peroxisome proliferation, and ...
Ruonan Li   +12 more
wiley   +1 more source

Publisher Correction: SLC2A1<sup>+</sup> tumour-associated macrophages spatially control CD8<sup>+</sup> T cell function and drive resistance to immunotherapy in non-small-cell lung cancer. [PDF]

open access: yesNat Cell Biol
Wang L   +20 more
europepmc   +1 more source

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

open access: yesiMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng   +15 more
wiley   +1 more source

Molecular crosstalk via exosomes in lung cancer progression

open access: yesInterdisciplinary Medicine, EarlyView.
“Molecular and theranostics roles of exosomes in Lung Cancer.” Abstract Exosomes play a critical role in lung cancer metastasis, facilitating tumor progression through intercellular communication between cancer cells and the tumor microenvironment. These nanosized extracellular vesicles carry bioactive molecules such as proteins, nucleic acids, and ...
Rajib Dhar   +3 more
wiley   +1 more source

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