Results 61 to 70 of about 138,356 (258)

Assessing the value of cultural ecosystem services in urban landscapes: evidence from Tai’an City, China

open access: yesFrontiers in Environmental Science
Cultural ecosystem services (CES) refer to the intangible benefits provided by ecosystems to enhance the quality of human life. As cultural services are an important part of ecosystem services, how to account for the value of cultural ecosystem services ...
Chongqing Xu   +8 more
doaj   +1 more source

HBV Infection Status Does Not Influence the Initial Metastatic Pattern and the Prognosis of Breast Cancer Patients with de novo and Relapsed Metastatic Disease

open access: yesJournal of Inflammation Research, 2022
Ningning Zhang,1 Dan Tao,2 Haike Lei,3 Qing Shao,1 Yumin Liu,4 Hua Long,4 Xiaohua Zeng1 1Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China; 2Department of Radiation Oncology, Chongqing ...
Zhang N   +6 more
doaj  

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

open access: yesAdvanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng   +13 more
wiley   +1 more source

Growth‐Like Swelling of 2D Precursors for Efficient Fabrication of Complex 3D Microstructures

open access: yesAdvanced Science, EarlyView.
The growth‐like swelling process fills photocured polymers into the elastomeric microstructures, inducing a significant swelling deformation of microstructures that can be maintained in the absence of solvents. The growth‐like swelling process breaks through the dependence of swelling deformation on the solvents, thereby expanding the application of 3D
Xinkai Zhu   +13 more
wiley   +1 more source

Custom-Molded Offloading Footwear Effectively Prevents Recurrence and Amputation, and Lowers Mortality Rates in High-Risk Diabetic Foot Patients: A Multicenter, Prospective Observational Study

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Xi Zhang,1,* Hongyan Wang,1,* Chenzhen Du,1 Xiaoyun Fan,2 Long Cui,3 Heming Chen,4 Fang Deng,5 Qiang Tong,6 Min He,7 Mei Yang,8 Xingrong Tan,9 Lin Li,10 Zerong Liang,11 Yaqin Chen,12 Deqing Chen,13 David G Armstrong,14 Wuquan Deng1 1Department of
Zhang X   +16 more
doaj  

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang   +11 more
wiley   +1 more source

Luteolin is an Effective Component of Platycodon grandiflorus in Promoting Wound Healing in Rats with Cutaneous Scald Injury

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Liang Wang,1,* Longjiao Hu,2,* Zhilian Peng,3 Honghong Cao,1 Danfeng Cao,4 Yiqin Long,4 Zhengyu Zou4 1Pharmacy Department, Traditional Chinese Medicine Hospital of Jiulongpo Distriction Chongqing, Chongqing, People’s Republic of China; 2Pharmacy ...
Wang L   +6 more
doaj  

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

open access: yesAdvanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang   +8 more
wiley   +1 more source

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo   +13 more
wiley   +1 more source

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang   +9 more
wiley   +1 more source

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