Results 101 to 110 of about 68,806 (303)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Research on Soft-switching Choppers in Maglev Trains

机车电传动, 2014
Optimal design for choppers in maglev trains were focused on with active auxiliary commutation circuit (AACC) techniques.Based on the operation principle and mathematical resonance analysis, it was shown that the resonance procedure of the proposed ...
LI, Yungang, WANG Ning, TAN Ying, CHENG Hu   +4 more
doaj  

Design of a chopper line for the CERN SPL [PDF]

, 2002
The SPL (Superconducting Proton Linac), a 2.2 GeV linac for high-intensity applications under study at CERN, requires a fast chopping at low energy of the H . beam.
Caspers, Friedhelm, Hanke, K, Lombardi, A M, Millich, Antonio, Mostacci, A, Paoluzzi, M, Vretenar, Maurizio   +6 more
core  

Mapping the CMB II: the second flight of the QMAP experiment

, 1998
We report the results from the second flight of QMAP, an experiment to map the cosmic microwave background near the North Celestial Pole. We present maps of the sky at 31 and 42 GHz as well as a measurement of the angular power spectrum covering the l ...
Amber D. Miller, Angelica de Oliveira-Costa, Baars J. W. M., Chini R., Lyman A. Page, Mark J. Devlin, Max Tegmark, Mezger P. G., Tom Herbig   +8 more
core   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Influence of Crowbar and Chopper Protection on DFIG during Low Voltage Ride Through

Energies, 2018
The energy sector is evolving rapidly, namely due to the increasing importance of renewable energy sources. The connection of large amounts of wind power generation poses new challenges for the dynamic voltage stability analysis of an electric power ...
Rita M. Monteiro Pereira, Adelino J. C. Pereira, Carlos Machado Ferreira, Fernando P. Maciel Barbosa   +3 more
doaj   +1 more source

A CMOS chopper amplifier

IEEE Journal of Solid-State Circuits, 1986
This paper presents a CMOS chopper amplifier realized with a 2nd order low-pass selective amplifier, using continuous-time filtering technique. The circuit has been integrated in a 3 ?m p-well low-voltage CMOS technology. The chopper DC gain is 32 dB with 200 Hz bandwidth.
Christian Enz, Eric A. Vittoz, F. Krummenacher   +2 more
openaire   +1 more source

Laser beam hydrocarbon detector [PDF]

, 1970
Portable instrument passes light from helium-neon laser at a wavelength of 3.39 microns through the atmosphere being monitored and measures attenuation of the laser beam.
Beam, B. H., Burrous, C. N., Jaynes, D. N.   +2 more
core   +1 more source

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

Advanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang, Xinyuan Ke, Andrew Heath, Richard J. Ball, Jiawei Xie, Jinchen Fan, Guisheng Li, Kevin Paine   +7 more
wiley   +1 more source