Results 31 to 40 of about 72,816 (336)
Quantum Beam Science, 2017 Neutron devices such as neutron detectors, optical devices including supermirror devices and 3He neutron spin filters, and choppers are successfully developed and installed at the Materials Life Science Facility (MLF) of the Japan Proton Accelerator ...
Kaoru Sakasai +30 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Emissivity measurements of reflective surfaces at near-millimeter wavelengths [PDF]
, 1995 We have developed an instrument for directly measuring the emissivity of reflective surfaces at near-millimeter wavelengths. The thermal emission of a test sample is compared with that of a reference surface, allowing the emissivity of the sample to be ...
Bock, J. J. +3 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Design, Construction and Evaluation of a Silage Corn Chopper Equipped with Electromotor Power Unit [PDF]
Journal of Agricultural Machinery, 2018 Introduction In most small and medium-size traditional animal farms, silage corn is chopped manually. In order to prepare appropriate chopper for small animal production firms, a small electrical powered chopper was designed and developed. Materials and
R Hadipiour Rokni +2 more
doaj +1 more source
Differential amplifier with regulator achieves high stability, low drift [PDF]
, 1961 When d-c signals are to be amplified, the usual approach is to use a direct-coupled circuit. The difficulty of maintaining sufficiently low drift in a direct-coupled configuration led to the development of chopper and chopper-stabilized circuits, where ...
Middlebrook, R. D., Taylor, A. D.
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Mesin Chopper untuk Meningkatkan Kualitas dan Kuantitas Pakan Usaha Ternak Kambing “Arrahman”
Warta LPMThe "Arrahman" partner is located in Kerten, Krincing Village, Secang District, Magelang manages around 200 to 300 goats. The process of preparing cattle fodder such as elephant grass and corn stalks is done manually using a knife.
Rany Puspita Dewi +2 more
doaj +1 more source