Results 31 to 40 of about 68,806 (303)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Auto-Phase-Locked Time-Resolved Luminescence Detection: Principles, Applications, and Prospects

open access: yesFrontiers in Chemistry, 2020
Time-resolved luminescence measurement is a useful technique which can eliminate the background signals from scattering and short-lived autofluorescence. However, the relative instruments always require pulsed excitation sources and high-speed detectors.
Qisheng Deng, Zece Zhu, Xuewen Shu
doaj   +1 more source

SPHERES, J\"ulich's High-Flux Neutron Backscattering Spectrometer at FRM II [PDF]

open access: yes, 2012
SPHERES (SPectrometer with High Energy RESolution) is a third-generation neutron backscattering spectrometer, located at the 20 MW German neutron source FRM II and operated by the Juelich Centre for Neutron Science.
Alefeld B.   +19 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Pengoptimalan Kinerja Pengereman Regeneratif Motor BLDC menggunakan Cascaded Boost Converter

open access: yesJurnal Elkomika, 2021
ABSTRAK Mesin Brushless Dircet Current (BLDC) digunakan pada kendaraan listrik karena memiliki torsi yang besar dan memungkinkan untuk pengereman regeneratif.
DANIEL RAHADIAN FIRMANTO   +3 more
doaj   +1 more source

Improved chopper circuit uses parallel transistors [PDF]

open access: yes, 1966
Parallel transistor chopper circuit operates with one transistor in the forward mode and the other in the inverse mode. By using this method, it acts as a single, symmetrical, bidirectional transistor, and reduces and stabilizes the offset ...

core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Mesin Chopper untuk Meningkatkan Kualitas dan Kuantitas Pakan Usaha Ternak Kambing “Arrahman”

open access: yesWarta LPM
The "Arrahman" partner is located in Kerten, Krincing Village, Secang District, Magelang manages around 200 to 300 goats. The process of preparing cattle fodder such as elephant grass and corn stalks is done manually using a knife.
Rany Puspita Dewi   +2 more
doaj   +1 more source

Single bunch selection for 162.5 MHz radio-frequency quadrupole accelerator

open access: yesHe jishu, 2021
BackgroundThe nuclear physics experiment terminal of the China initiative accelerator driven system (CiADS) accelerator device requires a single bunch. The frequency of radio-frequency quadrupole (RFQ) accelerator of CiADS facitily is 162.5 MHz, so the ...
MA Zhiguo   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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