Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism
Cell Proliferation, EarlyView.Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang +11 more
wiley +1 more source
Multimodal hard X-ray nanoprobe techniques for operando investigations of photovoltaic devices. [PDF]
J Synchrotron RadiatChoi E +7 more
europepmc +1 more source
CKAP4 Regulates ERS‐Induced Apoptosis in Osteoclasts Through FOXO3 in Periodontitis
Cell Proliferation, EarlyView.CKAP4 promotes the transcription of PERK via FOXO3 in OCs, thereby facilitating ER stress‐induced apoptosis. In periodontitis, the reduction of CKAP4 in OCs leads to decreased OC apoptosis, which exacerbates alveolar bone resorption. ABSTRACT Periodontitis is a prevalent oral disease characterised by chronic inflammation and irreversible alveolar bone ...
Jiayu Cheng +12 more
wiley +1 more source
Fluorescence-Detected Pump-Probe Spectroscopy for Artifact-Free Detection of Stokes Shift Dynamics. [PDF]
J Phys Chem LettHao H +5 more
europepmc +1 more source
Cell Proliferation, EarlyView.This study presents an NDs‐mediated localised combination strategy that integrates autophagy inhibition with low‐dose ATO sensitization, enabling effective tumour suppression while enhancing safety. NDs‐mediated autophagy blockade enhances ATO efficacy while minimising systemic toxicity, highlighting a promising approach for solid tumour treatment ...
Yiliu Wang +8 more
wiley +1 more source
Integrated transmission-reflection strong-field terahertz time-domain spectroscopy. [PDF]
iScienceLi J +10 more
europepmc +1 more source
Cell Proliferation, EarlyView.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Two-Photon Sub-Bandgap Photocurrent in Surface-Nanotextured Black Diamond Films for Solar Energy Conversion. [PDF]
ACS PhotonicsGirolami M +7 more
europepmc +1 more source
On the Maxumum Loop Gain of Chopper Amplifiers with a Make-before-break chopper
On the Maxumum Loop Gain of Chopper Amplifiers with a Make-before-break chopper論文(Article) 著者の一人（中津山）によって発表されたチョッパ増幅器の精密な解析法を用いて，中央短絡形チョッパを用いたチョッパ増幅器の負帰還量の限（(安定をそこなわずに帰還できる最大ループ利得）を計算し実測値と比較検討した。その結果両者は良く一致し，今までほっきりしなかった時定数が小さい場合の帰還量の限界が計算で求められ，この形のチョッパを用いた増幅器の安定性が明らかになった。これは，増幅器を設計する時の一つの基準になるであろう。 また，回路の時定数がチョッパ断続周期より大きい場合，誤差が少なく簡単に負帰還量の限界を求めることができる近似式が得られたので，これについても報告した。
openaire
Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi +5 more
wiley +1 more source