Results 121 to 130 of about 123,487 (278)

A Study of the Transfer Function of Chopper Amplifiers [PDF]

open access: yes, 1964
The chopper amplifier is frequently used in several types of d.c and a.c amplifiers as well as in d.c servomechanisms employing a.c control elements. In this paper the transfer function of the chopper amplifier is derived for a sinusoidal input signal ...
MIZUKAMI, Kōichi, HAYASHI, Shigenori
core  

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

open access: yesInterdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang   +3 more
wiley   +1 more source

Chopper offset stabilized current sensing amplifier

open access: yes
Current sensing is an indispensable technique employed across various uses, prominently in facilitating energy conservation, protection, and motor drives.
Low, Thien Shawn
core  

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

open access: yesInterdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong   +15 more
wiley   +1 more source

Bisphenol Analog‐Induced Cytotoxicity: Unraveling Endoplasmic Reticulum (ER) Stress and Apoptotic Pathways

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is increasingly replaced by structural analogs, yet their safety remains insufficiently characterized. This study investigated whether BPA and selected analogs, bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol P (BPP), and bisphenol E (BPE), induce cytotoxicity through activation of endoplasmic reticulum (ER) stress and ...
Rafia Afroze Rifa, Ramon Lavado
wiley   +1 more source

A 36 mu W Rail-to-Rail-Input Chopper Stabilized Amplifier using Correlated Double Sampling

open access: yes, 2013
This paper describes a chopper stabilized amplifier, obtained using an input chopper for modulation, an AC coupling for offset rejection and a correlated double sampling structure for demodulation, avoiding ripple spurs.
Baschirotto, A   +5 more
core  

Short‐Term 6PPD‐Q Exposure alters Tight‐Junction‐Related Gene Expression Without Acute Lethality in Japanese Medaka Oryzias latipes

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT 6PPD‐quinone (6PPD‐Q), a transformation product of the tire antioxidant 6PPD, causes acute mortality in several salmonid species, but its toxicity varies markedly among fish species. Disruption of vascular‐barrier integrity and inflammatory signaling has been proposed as a key mechanism of 6PPD‐Q toxicity.
Kyoshiro Hiki
wiley   +1 more source

Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal   +2 more
wiley   +1 more source

Realization of a Low-Distortion and Low-Noise CMOS Fully Differential Chopper Stabilized Amplifier

open access: yes, 2014
本論文主要目的在設計與實現低雜訊及低失真的CMOS全差動截波穩定型放大器,應用於放大感測器所輸出的低頻且微弱的訊號 (如生醫系統的感測器感測出的訊號),並實現一個二階GM-C帶通濾波器,以及外加一個低通濾波器以構成完整之感測器讀出電路。此電路主要是利用調變(Modulation)的技巧,使其能有效地降低放大器電路本身所產生的低頻雜訊以及輸入偏移電壓所造成的解析度誤差。本論文所實現出的電路,在利用CIC所提供的TSMC0.35um CMOS 2P4M製程技術來進行模擬。全差動截波穩定型放大器中之運算放大器,
Chen, Li Ju, 陳利如
core  

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