Results 41 to 50 of about 297,887 (290)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos   +5 more
wiley   +1 more source

A Chopper Stabilization Audio Instrumentation Amplifier for IoT Applications

open access: yesJournal of Low Power Electronics and Applications, 2020
A low-noise instrumentation amplifier dedicated to a nano- and micro-electro-mechanical system (M&NEMS) microphone for the use in Internet of Things (IoT) applications is presented. The piezoresistive sensor and the electronic interface are respectively,
Jamel Nebhen   +2 more
doaj   +1 more source

All‐Solution‐Processed HgTe Quantum Dot Photodetectors for Extended Short‐Wavelength Infrared Range Enhanced by Plasmonic ITO Nanocrystals

open access: yesAdvanced Functional Materials, EarlyView.
All‐solution‐processed, low‐cost extended short‐wavelength infrared photodetectors are realized by coupling colloidal HgTe quantum dots to plasmonic In2O3:Sn,F nanocrystals. Localized surface plasmon resonances boost and spectrally tailor light absorption between 1500 and 3000 nm, enabling responsivities above 40 A W−1.
Kseniia A. Sergeeva   +9 more
wiley   +1 more source

A Dynamic Instrumentation Amplifier for Low-Power and Low-Noise Biopotential Acquisition

open access: yesSensors, 2016
A low-power and low-noise dynamic instrumentation amplifier (IA) for biopotential acquisition is presented. A dynamic IA that can reduce power consumption with a timely piecewise power-gating method, and noise level with an alternating input and chopper ...
Jongpal Kim, Hyoungho Ko
doaj   +1 more source

Nanofiber‐Supported Decellularized Matrix Membrane Creates a Biomimetic Biochemical and Biophysical Niche for Intestinal Organoid Epithelium

open access: yesAdvanced Healthcare Materials, EarlyView.
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn   +7 more
wiley   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

open access: yesAdvanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen   +7 more
wiley   +1 more source

Ligand‐Mediated Shape Engineering of SWIR InAs Colloidal Quantum Dots for Photodetector Applications

open access: yesAdvanced Materials, EarlyView.
The table of contents: A robust ligand‐engineering strategy is introduced for SWIR InAs CQDs synthesized from amino‐arsine precursors. Bulky OA ligands induce controlled shape evolution, allowing access to >1700 nm absorption under mild conditions. Halide‐based inkification enables photodetectors with 19.1% EQE at 1300 nm and detectivity exceeding 1010
Taewan Kim   +5 more
wiley   +1 more source

Zero Drift Infrared Radiation Thermometer Using Chopper Stabilised Pre-Amplifier

open access: yesApplied Sciences, 2020
A zero-drift, mid–wave infrared (MWIR) thermometer constructed using a chopper stabilised operational amplifier (op-amp) was compared against an identical thermometer that utilised a precision op-amp.
Andrew D. Heeley   +2 more
doaj   +1 more source

Conductive Additives for Next‐Generation Batteries: Emphasizing the Potential of Bio‐Derived 3D Carbon Architectures at Electrode–Electrolyte Interfaces

open access: yesAdvanced Materials Interfaces, EarlyView.
3D conductive frameworks can maintain continuous electron transport, mechanical stability, and interfacial integrity, helping next‐generation batteries operate more efficiently. This Review examines their relevance to Si anodes, all‐solid‐state batteries, and dry‐processed electrodes, and highlights bio‐derived carbons as sustainable, structurally ...
SeoYoung Ha   +5 more
wiley   +1 more source

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