Results 61 to 70 of about 297,887 (290)
Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source
A Low-Noise Chopper Amplifier Designed for Multi-Channel Neural Signal Acquisition
IEEE Journal of Solid-State Circuits, 2019 This paper proposed the design of a low-noise, low total harmonic distortion (THD) chopper amplifier for neural signal acquisition. A dc servo loop (DSL) based on active Gm-C integrator is proposed to reject the electrode-dc-offset (EDO). Architecture of
Deng Luo, Milin Zhang, Zhihua Wang
semanticscholar +1 more source
Advanced Science, EarlyView.This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu +5 more
wiley +1 more source
Advanced Science, EarlyView.In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang +19 more
wiley +1 more source
A Novel Infrared Temperature Measurement with Dual Mode Modulation of Thermopile Sensor
Sensors, 2019 Superior to the traditional infrared temperature sensing architecture including infrared sensor and thermistor, we propose a novel sensing approach based on a single thermopile sensor with dual modes modulation.
Chih-Hsiung Shen +2 more
doaj +1 more source
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, EarlyView.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Advanced Science, EarlyView.Molecular dipole engineering in dendritic perylene diimide polymers through nitrogen‐rich heterocyclic linkers amplifies the built‐in electric field, enabling sub‐picosecond charge separation and efficient multi‐electron accumulation. This structure–dynamics–performance relationship establishes a versatile design strategy for high‐performance organic ...
Ying‐Xin Qiao +11 more
wiley +1 more source
Micromachines, 2018 This paper proposes a reconfigurable sensor analog front-end using low-noise chopper-stabilized delta-sigma capacitance-to-digital converter (CDC) for capacitive microsensors.
Hyungseup Kim +8 more
doaj +1 more source
Advanced Science, EarlyView.An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai +12 more
wiley +1 more source
A Low-power and Low-noise Multi-purpose Chopper Amplifier with High CMRR and PSRR
Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2020 In this article, by choosing and optimizing suitable structure in each stage, we have designed a multi-purpose low noise chopper amplifier. The proposed neural chopper amplifier with high CMRR and PSRR is suitable for EEG, LFP and AP signals while it has
Erwin H. T. Shad +2 more
semanticscholar +1 more source