Results 181 to 190 of about 299,019 (288)

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Spatial analysis of transcript and protein levels in skeletal muscle. [PDF]

STAR Protoc
Pisterzi P, Martinez Mir C, Dahri O, de Poorter I, Batlles Parera S, Dostanić M, Mastrangeli M, Mummery C, Geijsen N, Sage F.   +9 more
europepmc   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

1.79-GHz acquisition rate absolute distance measurement with lithium niobate electro-optic comb. [PDF]

Nat Commun
Qi Y, Jia X, Wang J, Yang W, Miao Y, Cai X, Wu G, Li Y.   +7 more
europepmc   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Ultrafast Electrical Charge Injection in Operating Perovskite Light-Emitting Diodes by Infrared Optical Control

Bakulin A, Gao R, Yuan Z, Yang B, Li L, Houot M, Huang M, Spencer B, Park S, Gasparini N, Snaith H, Chen Z.   +11 more
europepmc   +1 more source

Polarization-independent narrowband photodetection with plasmon-induced thermoelectric effect in a hexagonal array of Au nanoholes. [PDF]

Nanophotonics
Kim S, Kim S, Kim JY, Jeong TI, Song M, Kim S.   +5 more
europepmc   +1 more source

Fatigue of AM TiAl6V4: Probabilistic Modelling of the Size Influence as a Transfer Method From Test Specimen to Part

Fatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT This paper investigates the fatigue behavior of additively manufactured TiAl6V4 by comparing two specimen geometries with different highly stressed volumes. A fracture mechanical approach based on the El‐Haddad–Smith–Topper model is combined with defect analysis through X‐ray computed tomography.
Sebastian Mansky, Dirk Herzog, Ingomar Kelbassa   +2 more
wiley   +1 more source

Stimulated Raman Spectroscopy Using a Tunable Visible Broadband Probe Pulse Generated by Kerr Instability Amplification. [PDF]

Appl Spectrosc
Drouillard NG, Hammond TJ.
europepmc   +1 more source

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

Histopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin, Wenjian Cen, Qin Yan, Yangshan Chen, Chaoyun Huang, Yanfeng Feng, Neng Jiang   +6 more
wiley   +1 more source