Results 71 to 80 of about 16,903 (301)

Laser-excited fluorescence for measuring atmospheric pollution [PDF]

, 1975
System measures amount of given pollutant at specific location. Infrared laser aimed at location has wavelength that will cause molecules of pollutant to fluoresce.
Menzies, R. T.
core   +1 more source

Ultra‐Flexible Dual‐Band Organic Photodetectors for Visible and Near‐Infrared Sensing

Advanced Optical Materials, EarlyView.
An ultra‐flexible dual‐band organic photodetector with a total thickness of 5.6 µm for bio‐sensing is developed. It selectively detects visible and near‐infrared light with high sensitivity by switching the voltage. Peripheral oxygen saturation (SpO2) measurement is demonstrated using the device attached to a finger under a single light source by ...
Sachi Awakura, Hiroaki Jinno, Yusaku Tagawa, Ryota Fukuzawa, Masahito Takakuwa, Takao Someya, Tomoyuki Yokota   +6 more
wiley   +1 more source

A Novel Infrared Temperature Measurement with Dual Mode Modulation of Thermopile Sensor

Sensors, 2019
Superior to the traditional infrared temperature sensing architecture including infrared sensor and thermistor, we propose a novel sensing approach based on a single thermopile sensor with dual modes modulation.
Chih-Hsiung Shen, Shu-Jung Chen, Yi-Ting Guo   +2 more
doaj   +1 more source

A chopper amplifier with a low duty‐cycle sub‐sampling in the switched‐capacitor integrator for noise reduction

Electronics Letters, 2023
This letter presents a low‐noise implementation of the switched‐capacitor (SC) DC servo loop (DSL) in the capacitively coupled chopper instrumentation amplifier (CCIA).
Geng Mu, Liangjian Lyu, Dawei Ye, C.‐J. Richard Shi   +3 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source

Reconfigurable Sensor Analog Front-End Using Low-Noise Chopper-Stabilized Delta-Sigma Capacitance-to-Digital Converter

Micromachines, 2018
This paper proposes a reconfigurable sensor analog front-end using low-noise chopper-stabilized delta-sigma capacitance-to-digital converter (CDC) for capacitive microsensors.
Hyungseup Kim, Byeoncheol Lee, Yeongjin Mun, Jaesung Kim, Kwonsang Han, Youngtaek Roh, Dongkyu Song, Seounghoon Huh, Hyoungho Ko   +8 more
doaj   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source