Results 131 to 140 of about 235 (177)
Protein Science, Volume 35, Issue 9, September 2026.Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros +6 more
wiley +1 more source
Aging Cell, Volume 25, Issue 9, September 2026.Transcriptomic analysis using a rabbit glaucoma filtration surgery model, combined with in vitro experiments on human conjunctival fibroblasts, demonstrates that mitomycin C induces a senescence‐associated secretory phenotype (SASP)‐like state. These SASP‐like fibroblasts were selectively eliminated by the specific senolytic agent, highlighting their ...
Akitoshi Kimura +12 more
wiley +1 more source
FEBS Letters, Volume 600, Issue 16, Page 2262-2282, August 2026.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Hop domination in chordal bipartite graphs
Discussiones Mathematicae Graph Theory, 2023 Michael A. Henning +2 more
doaj +1 more source
In Situ Change in Contact Angle of a Sessile Droplet on a Magnetoactive Elastomer
Advanced Materials Interfaces, Volume 13, Issue 16, 18 August 2026.Contact angles of persistent μL$\mu{\rm L}$‐sized water droplets on a mechanically soft MAE surface under time varying magnetic fields differ from those of newly deposited droplets. The ability to quickly alter the material properties allows one to observe intriguing droplet‐material interactions.
Raphael Kriegl +3 more
wiley +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
Advanced Science, Volume 13, Issue 43, 3 August 2026.ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
Advanced Science, Volume 13, Issue 43, 3 August 2026.In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu +16 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, Volume 108, Issue 2, Page 287-300, August 1, 2026.ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn +10 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.Flowchart of the study design outlining target identification, validation, and subsequent functional and translational characterization. Abstract Background Skin cancer (SC) is among the most prevalent malignancies, yet causal circulating proteins and tractable therapeutic targets remain poorly defined.
Fan Shen +7 more
wiley +1 more source