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Immunobiology of Acute Chorioamnionitis. [PDF]

open access: yesFrontiers in Immunology, 2020
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the maternal fetal interface. It is a relatively common complication of pregnancy and can have devastating consequences including preterm labor, maternal infections,
Cappelletti, Monica   +2 more
core   +7 more sources

Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study [PDF]

open access: goldBMC Pregnancy and Childbirth, 2005
Background Chorioamnionitis is a common underlying cause of preterm birth (PTB). It is hypothesised that polymorphisms in immunoregulatory genes influence the host response to infection and subsequent preterm birth.
Heatley Susan L   +5 more
doaj   +6 more sources

Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes. [PDF]

open access: yesPLoS ONE, 2016
Chorioamnionitis (inflammation of the placenta and fetal membranes) and abnormal gastrointestinal colonization have been associated with an increased risk of sepsis and death in preterm infants, but whether chorioamnionitis causes abnormal pioneering ...
Kriti Puri   +5 more
doaj   +4 more sources

Chorioamnionitis and neonatal outcomes

open access: yesPediatric Research, 2021
Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth. Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes have been implicated to cause chorioamnionitis, but "sterile" inflammation appears to be more common.
Viral G. Jain   +3 more
openaire   +4 more sources

Acute histologic chorioamnionitis at term: nearly always noninfectious. [PDF]

open access: yesPLoS ONE, 2012
The link between histologic acute chorioamnionitis and infection is well established in preterm deliveries, but less well-studied in term pregnancies, where infection is much less common.We conducted a secondary analysis among 195 low-risk women with ...
Drucilla J Roberts   +6 more
doaj   +5 more sources

Understanding Host-Pathogen Interactions in Acute Chorioamnionitis Through the Use of Animal Models

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Inflammation of the chorion and/or amnion during pregnancy is called chorioamnionitis. Acute chorioamnionitis is implicated in approximately 40% of preterm births and has wide-ranging implications for the mother, fetus, and newborn.
Amanda Brosius Lutz   +4 more
doaj   +2 more sources

Association of clinical signs of chorioamnionitis with histological chorioamnionitis and neonatal outcomes

open access: yesThe Journal of Maternal-Fetal & Neonatal Medicine, 2022
Chorioamnionitis is a risk factor for fetal and neonatal outcomes. Therefore, predicting histological chorioamnionitis (HCA) and neonatal outcomes using clinical parameters could be helpful in management and preventing morbidities. To determine if parameters of clinical chorioamnionitis (CCA) would be associated with HCA and neonatal outcomes.
Samuel O, Ajayi   +8 more
openaire   +3 more sources

Day-to-day dynamics of fetal heart rate variability to detect chorioamnionitis in preterm premature rupture of membranes. [PDF]

open access: yesPLoS ONE
BackgroundChorioamnionitis is recognized as a major consequence of preterm premature rupture of membranes (PPROM), and a frequent cause of neonatal morbidity and mortality.
Aline Taoum   +5 more
doaj   +2 more sources

Determining the Maternal and Fetal Cellular Immunologic Contributions in Preterm Deliveries With Clinical or Subclinical Chorioamnionitis [PDF]

open access: yesInfectious Diseases in Obstetrics and Gynecology, 1997
Objective: Our purpose was to determine the maternal and fetal polymorphonuclear contributions to preterm histologic chorioamnionitis and whether this response differs in clinical chorioamnionitis when compared to cases without clinical ...
Gonik, B.   +4 more
core   +15 more sources

Detection of microbial cell-free DNA in maternal and umbilical cord plasma in patients with chorioamnionitis using next generation sequencing.

open access: yesPLoS ONE, 2020
BACKGROUND:Chorioamnionitis has been linked to spontaneous preterm labor and complications such as neonatal sepsis. We hypothesized that microbial cell-free (cf) DNA would be detectable in maternal plasma in patients with chorioamnionitis and could be ...
Russell G Witt   +8 more
doaj   +2 more sources

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