Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study [PDF]
Background Chorioamnionitis is a common underlying cause of preterm birth (PTB). It is hypothesised that polymorphisms in immunoregulatory genes influence the host response to infection and subsequent preterm birth.
Heatley Susan L+5 more
doaj +6 more sources
Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes. [PDF]
Chorioamnionitis (inflammation of the placenta and fetal membranes) and abnormal gastrointestinal colonization have been associated with an increased risk of sepsis and death in preterm infants, but whether chorioamnionitis causes abnormal pioneering ...
Kriti Puri+5 more
doaj +4 more sources
Immunobiology of Acute Chorioamnionitis. [PDF]
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the maternal fetal interface. It is a relatively common complication of pregnancy and can have devastating consequences including preterm labor, maternal infections,
Cappelletti, Monica+2 more
core +6 more sources
Acute histologic chorioamnionitis at term: nearly always noninfectious. [PDF]
The link between histologic acute chorioamnionitis and infection is well established in preterm deliveries, but less well-studied in term pregnancies, where infection is much less common.We conducted a secondary analysis among 195 low-risk women with ...
Drucilla J Roberts+6 more
doaj +6 more sources
Determining the Maternal and Fetal Cellular Immunologic Contributions in Preterm Deliveries With Clinical or Subclinical Chorioamnionitis [PDF]
Objective: Our purpose was to determine the maternal and fetal polymorphonuclear contributions to preterm histologic chorioamnionitis and whether this response differs in clinical chorioamnionitis when compared to cases without clinical ...
Gonik, B.+4 more
core +14 more sources
Apoptosis in the chorion laeve of term patients with histologic chorioamnionitis. [PDF]
OBJECTIVE: The balance between cell survival and cell death (apoptosis) is critical during development and may affect organ function. Apoptosis is accelerated in the presence of infection and inflammation in a variety of organ systems.
Auten, R, Herbert, W N P, Murtha, A P
core +5 more sources
The role of neutrophils in chorioamnionitis
Chorioamnionitis, commonly referred to as intrauterine infection or inflammation, is pathologically defined by neutrophil infiltration and inflammation at the maternal-fetal interface.
Cunling Zhang+5 more
doaj +3 more sources
The Consequences of Chorioamnionitis: Preterm Birth and Effects on Development [PDF]
Preterm birth is a major cause of perinatal mortality and long-term morbidity. Chorioamnionitis is a common cause of preterm birth. Clinical chorioamnionitis, characterised by maternal fever, leukocytosis, tachycardia, uterine tenderness, and preterm ...
Robert Galinsky+4 more
doaj +2 more sources
Chorioamnionitis: An Update on Diagnostic Evaluation
Chorioamnionitis remains a major cause of preterm birth and maternal and neonatal morbidity. We reviewed the current evidence for the diagnostic tests of chorioamnionitis and how this relates to clinical practice today.
Sean W. D. Carter+7 more
doaj +3 more sources
Maternal C-reactive protein for detection of chorioamnionitis: an appraisal. [PDF]
Premature delivery is still a significant problem in obstetrics, and chorioamnionitis is an unwelcome complication. C-reactive protein (CRP) is a circulating marker of low-grade inflammation and the role of its measurement in clinical practice remains ...
Wiwanitkit, Viroj
core +5 more sources