Immunobiology of Acute Chorioamnionitis. [PDF]
Frontiers in Immunology, 2020Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the maternal fetal interface. It is a relatively common complication of pregnancy and can have devastating consequences including preterm labor, maternal infections,
Cappelletti, Monica+2 more
core +7 more sources
Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study [PDF]
BMC Pregnancy and Childbirth, 2005Background Chorioamnionitis is a common underlying cause of preterm birth (PTB). It is hypothesised that polymorphisms in immunoregulatory genes influence the host response to infection and subsequent preterm birth.
Heatley Susan L+5 more
doaj +6 more sources
Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes. [PDF]
PLoS ONE, 2016Chorioamnionitis (inflammation of the placenta and fetal membranes) and abnormal gastrointestinal colonization have been associated with an increased risk of sepsis and death in preterm infants, but whether chorioamnionitis causes abnormal pioneering ...
Kriti Puri+5 more
doaj +4 more sources
Chorioamnionitis and neonatal outcomes
Pediatric Research, 2021Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth. Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes have been implicated to cause chorioamnionitis, but "sterile" inflammation appears to be more common.
Viral G. Jain+3 more
openaire +4 more sources
Acute histologic chorioamnionitis at term: nearly always noninfectious. [PDF]
PLoS ONE, 2012The link between histologic acute chorioamnionitis and infection is well established in preterm deliveries, but less well-studied in term pregnancies, where infection is much less common.We conducted a secondary analysis among 195 low-risk women with ...
Drucilla J Roberts+6 more
doaj +5 more sources
Understanding Host-Pathogen Interactions in Acute Chorioamnionitis Through the Use of Animal Models
Frontiers in Cellular and Infection Microbiology, 2021Inflammation of the chorion and/or amnion during pregnancy is called chorioamnionitis. Acute chorioamnionitis is implicated in approximately 40% of preterm births and has wide-ranging implications for the mother, fetus, and newborn.
Amanda Brosius Lutz+4 more
doaj +2 more sources
Chorioamnionitis is a risk factor for fetal and neonatal outcomes. Therefore, predicting histological chorioamnionitis (HCA) and neonatal outcomes using clinical parameters could be helpful in management and preventing morbidities. To determine if parameters of clinical chorioamnionitis (CCA) would be associated with HCA and neonatal outcomes.
Samuel O, Ajayi+8 more
openaire +3 more sources
Day-to-day dynamics of fetal heart rate variability to detect chorioamnionitis in preterm premature rupture of membranes. [PDF]
PLoS ONEBackgroundChorioamnionitis is recognized as a major consequence of preterm premature rupture of membranes (PPROM), and a frequent cause of neonatal morbidity and mortality.
Aline Taoum+5 more
doaj +2 more sources
Determining the Maternal and Fetal Cellular Immunologic Contributions in Preterm Deliveries With Clinical or Subclinical Chorioamnionitis [PDF]
Infectious Diseases in Obstetrics and Gynecology, 1997Objective: Our purpose was to determine the maternal and fetal polymorphonuclear contributions to preterm histologic chorioamnionitis and whether this response differs in clinical chorioamnionitis when compared to cases without clinical ...
Gonik, B.+4 more
core +15 more sources
BACKGROUND:Chorioamnionitis has been linked to spontaneous preterm labor and complications such as neonatal sepsis. We hypothesized that microbial cell-free (cf) DNA would be detectable in maternal plasma in patients with chorioamnionitis and could be ...
Russell G Witt+8 more
doaj +2 more sources