Results 51 to 60 of about 28,641 (340)

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

open access: yesAdvanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li   +9 more
wiley   +1 more source

On-field Gross Morphology Evaluation of Dromedary Camel (Camelus dromedarius) Fetal Membranes

open access: yesAnimals
The dromedary camel (Camelus dromedarius) fetal membranes, commonly referred to as “the placenta”, are epitheliochorial, diffuse, and microcotyledonary, similarly to the mare’s placenta.
Davide Monaco   +5 more
doaj   +1 more source

Using Noninvasive Genetic Sampling to Survey Rare Butterfly Populations

open access: yesInsects, 2019
Advances in nondestructive genetic sampling techniques continue to offer new opportunities for studying organisms, particularly those of conservation concern where more traditional invasive sampling methods are often not available.
Caroline Storer   +3 more
doaj   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

open access: yesAdvanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao   +12 more
wiley   +1 more source

Chorion ultrastructure of some fish eggs from the South-East Atlantic

open access: yes, 1987
13 pages, 21 figures, 2 tablesThe chorion ultrastructure of the eggs of some teleost fish from the South-East Atlantic was studied by means of a scanning electron microscope.
M.-P. Olivar, Olivar, M. Pilar
core   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

open access: yesAdvanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta   +6 more
wiley   +1 more source

In vivo Assessment of Supra-Cervical Fetal Membrane by MRI 3D CISS: A Preliminary Study

open access: yesFrontiers in Physiology, 2020
In approximately 8% of term births and 33% of pre-term births, the fetal membrane (FM) ruptures before delivery. In vitro studies of FMs after delivery have suggested the series of events leading to rupture, but no in vivo studies have confirmed this ...
Wenxu Qi   +19 more
doaj   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

The Lipid Phosphate Phosphatase Wunen Promotes Eggshell Formation and Is Essential for Fertility in Drosophila

open access: yesBiology, 2023
The eggshell that surrounds insect eggs acts as a barrier, protecting against biotic factors and desiccation. The eggshell is a multi-layered structure which is synthesised by the somatic follicle cells that surround the developing oocyte.
Amrita Mukherjee   +2 more
doaj   +1 more source

Failure to obtain reliable retrospective determination of chorion type using parent information: Confirmation with French data [PDF]

open access: yes, 2004
International audienceFollowing the Derom et al. paper recently published in Twin Research (2003, 6,19-21), we investigated our French sample, studying the retrospective validity of information given by parents to determine the chorion type of their ...
Spitz, E, Carlier, Michèle
core   +1 more source

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