Results 61 to 70 of about 2,246,140 (208)
Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community
Prenatal Diagnosis, EarlyView.ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum +4 more
wiley +1 more source
Study of comparison of obtaining transcervical chorionic villus sampling by needle and infant feeding tube [PDF]
, 2018 The developmental abnormalities are on rise, due to increased exposure to environmental toxins and intervention in reproductive process and so the risk to any pregnant couple of having up to 5% live-born infant with a chromosomal abnormality or ...
Jyoti Kiran Kohli
core +1 more source
CHORIONIC VILLUS SAMPLING: A SAFE TOOL FOR PRENATAL DIAGNOSIS OF GENETIC DISORDERS
Pakistan Armed Forces Medical Journal, 2009 Objectives: To determine the safety and efficacy of chorionic villus sampling (CVS) for early prenatal diagnosis of genetic disorders. Study Design: Descriptive study.
Nadra Sultana, Zartaj Hayat, Iffat Nasim
doaj +2 more sources
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To examine if and where ethnic and socioeconomic inequalities arise within the English NHS prenatal screening pathway by investigating associations between ethnicity, socioeconomic deprivation, screening test type, further testing uptake, and pregnancy outcomes.
Michelle Peter +3 more
wiley +1 more source
Impact of chorionic villus sampling volume on time to result and pregnancy management
The Journal of Maternal-Fetal & Neonatal MedicineObjective To evaluate the association between low-volume chorionic villus sampling (CVS) and delay in patient care.Methods This is a retrospective cohort study of patients who underwent CVS from 8/19/2019 to 12/31/2022 in a single center.
Emily Lee +3 more
doaj +1 more source
Non‐Invasive Prenatal Diagnosis of Haemoglobinopathies: From Concept to Clinical Reality
Prenatal Diagnosis, EarlyView.ABSTRACT Haemoglobinopathies are the most prevalent monogenic disorders worldwide, contributing significantly to childhood morbidity and mortality. Preventive strategies, including carrier screening and prenatal diagnosis, have successfully reduced disease incidence in regions with established programmes.
Irene Leonidou +7 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To evaluate the analytical and clinical performance of fetal fraction (FF) enriched genome‐wide noninvasive prenatal testing (GW‐NIPT) for the detection of clinically relevant copy number variants (CNVs) down to 1 Mb. Methods We retrospectively analyzed 10,501 singleton pregnancies tested with FF enrichment‐based GW‐NIPT between ...
Karmen Vaiküll +6 more
wiley +1 more source
Procedure-related risk of miscarriage following chorionic villus sampling and amniocentesis [PDF]
, 2019 Objective: The objective of our study was to estimate the procedure-related risks of miscarriage following CVS and amniocentesis in a large unselected screened and to determine whether these risks are consistent with those reported in systematic reviews ...
Geris, S. +4 more
core +1 more source
The complications caused by chorionic villus sampling and amniocentesis in mothers referred to perinatology clinic [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i ĪrānIntroduction: After screening tests, CVS and amniotic fluid sampling (amniocentesis) are two definitive methods for prenatal diagnosis of chromosomal abnormalities and genetic diseases.
Shima Nasirnia +5 more
doaj +1 more source