Results 201 to 210 of about 91,251 (315)

RNA‐based CLEM (RCLEM) bridging RNA localisation and ultrastructural mapping in 3D

open access: yesJournal of Microscopy, Volume 303, Issue 1, Page 120-131, July 2026.
Abstract Spatial transcriptomics and in situ hybridisation techniques have become essential for contextualising single‐cell RNA sequencing (scRNA‐seq) data by mapping cell type– and state–specific mRNA expression within intact tissues. Beyond validating scRNA‐seq predictions, these spatial methods provide critical insight into the localisation of ...
Daan Verhaege   +8 more
wiley   +1 more source

Role of BDNF in form-deprivation myopia progression in guinea pigs. [PDF]

open access: yesFront Immunol
Xie RY   +7 more
europepmc   +1 more source

miniMORPH: A Morphometry Pipeline for Low‐Field MRI in Infants

open access: yesHuman Brain Mapping, Volume 47, Issue 9, June 15, 2026.
miniMORPH is a fully automated pipeline for extracting regional brain volumes from ultra‐low‐field (0.064 T) infant MRI without super‐resolution. Benchmarking against high‐field references shows it preserves between‐subject variation and yields face‐valid developmental and birthweight‐related effects, enabling scalable neurodevelopmental morphometry ...
Chiara Casella   +18 more
wiley   +1 more source

Longitudinal changes of choroid plexus volumes and MRI ratios in multiple sclerosis. [PDF]

open access: yesBrain Commun
Krieger B   +8 more
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

open access: yesAdvanced Science, Volume 13, Issue 34, 19 June 2026.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul   +12 more
wiley   +1 more source

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