Results 11 to 20 of about 150,893 (261)

Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors

Journal of Neuro-Oncology, 2020
Purpose Choroid plexus tumors comprise of choroid plexus papilloma (CPP, WHO grade I), atypical choroid plexus papilloma (aCPP, WHO grade II) and choroid plexus carcinoma (CPC, WHO grade III).
Christian Thomas, Uwe Kordes, Martin Hasselblatt   +2 more
exaly   +2 more sources

A probabilistic deep learning approach for choroid plexus segmentation in autism spectrum disorder [PDF]

NPP-Digital Psychiatry and Neuroscience
The choroid plexus serves as the primary barrier between the brain’s blood and cerebrospinal fluid and mediates neuroimmune function. A subset of individuals with autism spectrum disorder (ASD) may exhibit morphological alterations of the choroid plexus.
Filippo Bargagna, Thomas M. Morin, Ya-Chin Chen, Ylind Lila, Chieh-En J. Tseng, Maria F. Santarelli, Nicola Vanello, Christopher J. McDougle, Jacob M. Hooker, Nicole R. Zürcher   +9 more
doaj   +2 more sources

Choroid plexus volume in brain disorders: a systematic review [PDF]

Fluids and Barriers of the CNS
Background The choroid plexus is a highly vascularized structure located in the lateral, third, and fourth ventricles of the brain. Recent studies suggest that volumetric changes in choroid plexus volume are associated with progression in various brain ...
Derya Tireli, Jeppe Romme Christensen, Tina Nørgaard Munch, Nanna MacAulay, Henrik Bo Wiberg Larsson, Jonathan Frederik Carlsen, Stig Praestekjaer Cramer   +6 more
doaj   +2 more sources

Morphology of the murine choroid plexus: Attachment regions and spatial relation to the subarachnoid space

Frontiers in Neuroanatomy, 2022
The choroid plexus has recently been identified as a possible migration route for peripheral immune cells into the central nervous system. For future investigation of this route, profound knowledge of the morphology of the murine choroid plexus is a ...
Theresa Greiner, Katerina Manzhula, Louise Baumann, Hannes Kaddatz, Jens Runge, Jens Runge, Jonas Keiler, Markus Kipp, Sarah Joost   +8 more
doaj   +1 more source

Dysregulation of brain and choroid plexus cell types in severe COVID-19

Nature, 2021
Although SARS-CoV-2 primarily targets the respiratory system, patients with and survivors of COVID-19 can suffer neurological symptoms1–3. However, an unbiased understanding of the cellular and molecular processes that are affected in the brains of ...
Andrew C. Yang, Fabian Kern, P. M. Losada, M. Agam, Christina A. Maat, G. Schmartz, Tobias Fehlmann, Julian A. Stein, N. Schaum, Davis P. Lee, K. Calcuttawala, Ryan T. Vest, D. Berdnik, Nannan Lu, Oliver Hahn, D. Gate, M. W. McNerney, D. Channappa, I. Cobos, N. Ludwig, W. Schulz-Schaeffer, A. Keller, T. Wyss‐Coray   +22 more
semanticscholar   +1 more source

Choroid plexus APP regulates adult brain proliferation and animal behavior

Life Science Alliance, 2021
Adult mouse choroid plexus shows elevated APP expression. sAPPα secreted into the CSF modulates neurogenic niche proliferation, whereas choroid plexus expression of fAD APP mutants leads to reduced niche proliferation, deficits in hippocampus synaptic ...
Karen Arnaud, Vanessa Oliveira Moreira, Jean Vincent, Glenn Dallerac, Chantal Dubreuil, Edmond Dupont, Max Richter, Ulrike C Müller, Laure Rondi-Reig, Alain Prochiantz, Ariel A Di Nardo   +10 more
doaj   +1 more source

PATHOGENESIS OF ALZHEIMER’S DISEASE: INVOLVEMENT OF THE CHOROID PLEXUS

Alzheimer's & Dementia, 2023
The choroid plexus (ChP) produces and is bathed in the cerebrospinal fluid (CSF), which in aging and Alzheimer's disease (AD) shows extensive proteomic alterations including evidence of inflammation.
M. Čarna, I. Onyango, S. Katina, D. Holub, Jan S. Novotný, Markéta Nezvedová, Durga Jha, Z. Nedelska, V. Lacovich, T. V. Vyvere, R. Houbrechts, K. Garcia-Mansfield, Ritin Sharma, V. David-Dirgo, M. Vyhnálek, K. Texlová, H. Chaves, N. Bakkar, L. Pertierra, Mojmír Vinkler, H. Markova, J. Laczó, K. Sheardová, M. Hortová-Kohoutková, J. Frič, G. Forte, P. Kaňovský, S. Belaskova, J. Damborský, J. Hort, Nicholas T. Seyfried, R. Bowser, G. Sevlever, R. Rissman, Richard A Smith, M. Hajdůch, P. Pirrotte, Z. Spáčil, Eric B. Dammer, Clara Limbäck-Stokin, G. Stokin   +40 more
semanticscholar   +1 more source

Choroid Plexus Aquaporins in CSF Homeostasis and the Glymphatic System: Their Relevance for Alzheimer’s Disease

International Journal of Molecular Sciences, 2023
The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is known to be impaired in neurological disorders, including Alzheimer’s disease (AD).
Cristina Municio, Laura Carrero, D. Antequera, E. Carro   +3 more
semanticscholar   +1 more source

Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited

Fluids and Barriers of the CNS, 2022
Cerebrospinal fluid (CSF) envelops the brain and fills the central ventricles. This fluid is continuously replenished by net fluid extraction from the vasculature by the secretory action of the choroid plexus epithelium residing in each of the four ...
N. MacAulay, R. Keep, T. Zeuthen
semanticscholar   +1 more source

Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice

Toxicology Reports, 2021
Sepsis-associated encephalopathy (SAE) is characterized as diffuse brain dysfunction in patients with excessive systemic inflammatory reaction to an infection.
Atsuyoshi Shimada, Sanae Hasegawa-Ishii
doaj   +1 more source