Results 51 to 60 of about 80,377 (269)

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transporters

Frontiers in Neuroscience, 2015
Thyroid hormones (THs) are key players in regulating brain development. In humans, insufficient THs during gestation can lead to cretinism and mental retardation.
Samantha J. Richardson, Roshen C. Wijayagunaratne, Damian G. D'Souza, Veerle M. Darras, Stijn L. J. Van Herck   +4 more
doaj   +1 more source

Choroid Plexus Pathophysiology

Annual Review of Pathology: Mechanisms of Disease
This review examines the roles of the choroid plexus (ChP) in central nervous system (CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic potential. Structural changes in the human ChP have been reported across various diseases in case reports and descriptive work, but studies have yet to pin down the physiological ...
Courtney, Ya’el, Hochstetler, Alexandra, Lehtinen, Maria K.   +2 more
openaire   +2 more sources

Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions

Cell Reports
Summary: The choroid plexus is a major site for cerebrospinal fluid (CSF) production, characterized by a multiciliated epithelial monolayer that regulates CSF production.
Suifang Mao, Rui Song, Shibo Jin, Song Pang, Aleksandra Jovanovic, Adam Zimmerman, Peng Li, Xinying Wu, Michael F. Wendland, Kerry Lin, Wei-Chi Chen, Semil P. Choksi, Gang Chen, Michael J. Holtzman, Jeremy F. Reiter, Ying Wan, Zhenyu Xuan, Yang K. Xiang, C. Shan Xu, Srigokul Upadhyayula, Harald F. Hess, Lin He   +21 more
doaj   +1 more source

From Rigid to Soft Robotic Approaches for Neuroendoscopy

Advanced Robotics Research, EarlyView.
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday, Irena Zubak, Andreas Raabe, Josie Hughes   +3 more
wiley   +1 more source

Atypical choroid plexus papilloma: Diagnosis and differentials: A case report

SAGE Open Medical Case Reports
Atypical choroid plexus papilloma is a rare World Health Organization grade 2 intraventricular tumor arising from the epithelium of the plexus choroid with intermediate clinical-pathological features between the benign choroid plexus papilloma and the ...
H. Andour, S. Ben El Hend, C. Mandour, M. Allaoui, A. Fikri   +4 more
doaj   +1 more source

Choroid Plexus Microstructural Alterations Link Glymphatic Dysfunction and White Matter Degeneration in Parkinson's Disease. [PDF]

CNS Neurosci Ther
This study investigates the role of choroid plexus (CP) microstructural alterations in Parkinson's disease (PD), using free‐water corrected diffusion tensor imaging (FW‐DTI). Elevated CP diffusion metrics were linked to glymphatic dysfunction, corpus callosum degeneration, and worsened motor and cognitive performance in PD patients.
Zhou S, Zhen Z, Lai C, Huang P, Sun Z, Yang T, Yu F, Chen W, Zuo Z, Chen W.   +9 more
europepmc   +2 more sources

Malignant progression in choroid plexus papillomas

, 2007
Object. Malignant progression of choroid plexus papillomas has been occasionally reported, but this issue has not yet been systematically addressed. Methods.
Paulus, Werner, Wolff, Johannes E., Hasselblatt, Martin, Wrede, Brigitte, Jeibmann, Astrid, Peters, Ove   +5 more
core   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Immunohistochemical analysis of CDX2 expression in normal choroid plexus epithelium and choroid plexus tumors [PDF]

, 2009
Background: The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a ...
Mugler, M., Beschorner, R., Meyermann, R., Schittenhelm, J., Mittelbronn, M.   +4 more
core