Results 31 to 40 of about 8,084 (192)

Cytokeratin 7 and 20 Expression in Choroid Plexus Tumors: Utility in Differentiating These Neoplasms from Metastatic Carcinomas [PDF]

Modern Pathology, 2000
Tumors derived from choroid plexus epithelium are uncommon and may exhibit a wide variety of histologic patterns. They often are difficult to distinguish from metastatic carcinomas. Previous studies that addressed this issue yielded conflicting results.
K A, Gyure, A L, Morrison
openaire   +2 more sources

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups [PDF]

, 2018
BACKGROUND: Choroid plexus tumors are intraventricular neoplasms derived from the choroid plexus epithelium. A better knowledge of molecular factors involved in choroid plexus tumor biology may aid in identifying patients at risk for recurrence. METHODS:
Witten A, Thomas C, Hartung S, Keyvani K, Pietsch T, Pfister SM, Monoranu CM, Korshunov A, Wolff JE, Paulus W, Beschorner R, Jones DT, Grundy RG, Kordes U, Olar A, Hovestadt V, Hauser, Péter, von Deimling A, Jeibmann A, Ruland V, Capper D, Mittelbronn M, Varlet P, Felsberg J, Bewerunge-Hudler M, Bergmann M, Hasselblatt M, Sill M   +27 more
core   +1 more source

Single-nucleus RNA-seq dissection of choroid plexus tumor cell heterogeneity

The EMBO Journal
The genomic, genetic and cellular events regulating the onset, growth and survival of rare, choroid plexus neoplasms remain poorly understood. Here, we examine the heterogeneity of human choroid plexus tumors by single-nucleus transcriptome analysis of ...
Anthony D Hill, Konstantin Okonechnikov, Marla K Herr, Christian Thomas, Supat Thongjuea, Martin Hasselblatt, Annarita Patrizi   +6 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Surgical management of huge neonatal brain tumor - Town hospital Experience [PDF]

Pan Arab Journal of Neurosurgery
BackgroundBrain tumors are uncommon in infants younger than 6 months old. The most common types of neonatal brain tumors include teratomas, astrocytomas, embryonal neoplasms, choroid plexus tumors, craniopharyngiomas, gangliogliomas, ependymal tumors ...
Ahmed Osama El Ghannam, Mariam Abd Elrasheed Ghanem, Ahmed Mustafa Abd Elsalam Abd Elsalam   +2 more
doaj   +1 more source

From Rigid to Soft Robotic Approaches for Neuroendoscopy

Advanced Robotics Research, EarlyView.
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday, Irena Zubak, Andreas Raabe, Josie Hughes   +3 more
wiley   +1 more source

Immunohistochemical analysis of CDX2 expression in normal choroid plexus epithelium and choroid plexus tumors [PDF]

, 2009
Background: The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a ...
Mugler, M., Beschorner, R., Meyermann, R., Schittenhelm, J., Mittelbronn, M.   +4 more
core  

Expression of Collagen VI, Anticollagenase, Laminin, MM9, Claudins 1 and 5, N and E Cadherins in Choroid Plexus Tumors

, 2023
Background: CPTs are rare intraventricular papillary neoplasms derived from the choroid plexus epithelium. Anti-collagenase and extracellular matrix which have not been expressed in brain tumors. Objective: The purpose of this study was to ...
Laura Chavez Macias, Alma Ortiz Plata, Carmen Rubio*, Martha Lilia Tena-Suck, Erick Gómez-Apo   +4 more
core   +1 more source

Cerebrospinal fluid secretion by the choroid plexus

, 2013
The choroid plexus epithelium is a cuboidal cell monolayer, which produces the majority of the cerebrospinal fluid. The concerted action of a variety of integral membrane proteins mediates the transepithelial movement of solutes and water across the ...
Brown, Peter, Praetorius, Jeppe, Brown, Peter D., Damkier, Helle H.   +3 more
core   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source