Results 81 to 90 of about 1,220,424 (119)

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez, Kayla Etienne, Long Di, Valerie Martinez‐Torres, Andrew Rosenberg, Sakir H. Gultekin, Aditi Dhir, Bradley Gampel, Heather J. McCrea   +8 more
wiley   +1 more source

Choroid plexus in developmental and evolutionary perspective

, 2014
The blood-cerebrospinal fluid boundary is present at the level of epithelial cells of the choroid plexus. As one of the sources of the cerebrospinal fluid, the choroid plexus plays an important role during brain development and function.
Vladimir eKorzh, Brent eBill
core   +1 more source

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups [PDF]

, 2018
BACKGROUND: Choroid plexus tumors are intraventricular neoplasms derived from the choroid plexus epithelium. A better knowledge of molecular factors involved in choroid plexus tumor biology may aid in identifying patients at risk for recurrence. METHODS:
Witten A, Thomas C, Hartung S, Keyvani K, Pietsch T, Pfister SM, Monoranu CM, Korshunov A, Wolff JE, Paulus W, Beschorner R, Jones DT, Grundy RG, Kordes U, Olar A, Hovestadt V, Hauser, Péter, von Deimling A, Jeibmann A, Ruland V, Capper D, Mittelbronn M, Varlet P, Felsberg J, Bewerunge-Hudler M, Bergmann M, Hasselblatt M, Sill M   +27 more
core   +1 more source

Clinical Features and Prognostic Risk Factors of Choroid Plexus Tumors in Children

Chinese Medical Journal, 2018
Background: Decision-making concerning the treatment of choroid plexus tumor (CPT) in pediatric patients remains a topic of considerable debate. The aim of this work was to describe clinical features and prognostic risk factors of CPT in the pediatric ...
Wen-Jian-Long Zhou, Xi Wang, Jia-Yi Peng, Shun-Chang Ma, Dai-Nan Zhang, Xiu-Dong Guan, Jin-Fu Diao, Jian-Xing Niu, Chun-De Li, Wang Jia   +9 more
doaj   +1 more source

Outcomes of adult patients with Li‐Fraumeni syndrome and myeloid neoplasms

Cancer, Volume 132, Issue 19, 1 October 2026.
Abstract Background Li‐Fraumeni syndrome (LFS) is an inherited cancer predisposition syndrome. Hematologic malignancies are not considered LFS defining tumors, however, both acute lymphoblastic leukemia and therapy‐related myeloid neoplasms (MNs) in LFS are described. Treatment approaches and outcomes of MN in LFS need further evaluation.
Jayastu Senapati, Hiam M. Abdel‐Salam, Vladislav D. Jdanov, Sanam Loghavi, Ashley Woodson, Jessica Corredor, Gautam Borthakur, Naval G. Daver, Tapan M. Kadia, Koichi Takahashi, Yesid Alvarado, Naveen Pemmaraju, Uday R. Popat, Elizabeth J. Shpall, Farhad Ravandi, Florencia McAllister, Najat C. Daw, Guillermo Garcia‐Manero, Banu K. Arun, Courtney D. DiNardo   +19 more
wiley   +1 more source

Overactivation of SHH signaling induces a cascade of dedifferentiation and oncogenesis in a new mouse model for choroid plexus carcinoma

Acta Neuropathologica Communications
Choroid Plexus tumors constitute 10–20% of brain tumors in infancy. Among these, Choroid Plexus Carcinomas (CPC) are highly aggressive and result in poor survival. Details on tumor initiation and oncogenic events remain largely unknown, aside from a high
Levke-Sophie Peter, Lea Altendorf, Karoline Hack, Vanessa Thaden, Carolin Göbel, Beatrix Mahnke, Christian Krebs, Saskia-L. Jauch-Speer, Uwe R. Kordes, Denise Obrecht-Sturm, Christian Thomas, Ulrich Schüller, Melanie Schoof   +12 more
doaj   +1 more source

Survival of infants ≤24 months of age with brain tumors: A population-based study using the SEER database.

PLoS ONE, 2019
INTRODUCTION:Brain tumors are the most common solid malignancy and leading cause of cancer-related deaths in infants. Current epidemiological data is limited by low numbers of reported cases.
Claire Faltermeier, Timothy Chai, Sharjeel Syed, Nathan Lau, Lior Elkaim, George Ibrahim, Anthony Wang, Alexander Weil, Anne Bendel, Aria Fallah, Albert Tu   +10 more
doaj   +1 more source

Posterior fossa choroid plexus papilloma with focal ependymal differentiation in an adult patient: A case report and literature review

Radiology Case Reports, 2019
Choroid plexus papillomas (CPPs) are rare neoplasms classified as World Health Organization grade I tumors. CPPs containing other tissues have occasionally been documented in the literature.
Shu Matsushita, MD, Taro Shimono, MD, PhD, Takeo Goto, MD, PhD, Satoshi Doishita, MD, PhD, Yuko Kuwae, MD, Yukio Miki, MD, PhD   +5 more
doaj   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Dysphonia As an Uncommon Presentation of Pontocerebellar Choroid Plexus Papilloma

Acta Clinica Croatica, 2015
A case is presented of a patient with dysphonia, hearing loss and ataxia due to vestibulocochlear and vagal nerve compression by choroid plexus papilloma in the cerebellopontine angle.
Krešimir Rotim, Tomislav Sajko, Marina Zmajević, Ilijana Šumonja, Marko Grgić   +4 more
doaj