Results 71 to 80 of about 2,270 (207)

The Hippo signalling pathway and its impact on eye diseases

Journal of Cellular and Molecular Medicine, Volume 28, Issue 8, April 2024.
Abstract The Hippo signalling pathway, an evolutionarily conserved kinase cascade, has been shown to be crucial for cell fate determination, homeostasis and tissue regeneration. Recent experimental and clinical studies have demonstrated that the Hippo signalling pathway is involved in the pathophysiology of ocular diseases.
Yuxiang Du
wiley   +1 more source

Anomalias congênitas do disco óptico associadas à doença de Moyamoya: relato de caso Congenital anomalies of the optic disc associated with Moyamoya disease: case report

Arquivos de Neuro-Psiquiatria, 2005
As anomalias congênitas do disco óptico podem estar associadas a anormalidades vasculares intracranianas. Relatamos o caso de um paciente de 9 anos com anomalia do disco óptico tipo morning glory em um olho e coloboma do disco óptico e coróide ...
Ramon Coral Ghanem, André Gustavo Bombana Nicoletti, Leonardo Provetti Cunha, Mario Luiz Ribeiro Monteiro   +3 more
doaj   +1 more source

Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development [PDF]

, 2012
Molecular oxygen is essential for the development, growth and survival of multicellular organisms. Hypoxic microenvironments and oxygen gradients are generated physiologically during embryogenesis and organogenesis.
Abrahams, S., Ali, R. R., Bainbridge, J. W., Fruttiger, M., Georgiadis, A., Lange, C. A., Luhmann, U. F., Maxwell, P. H., Mowat, F. M., Powner, M. B., Sayed, H., Smith, A. J., Sowden, J. C., West, E. L.   +13 more
core   +1 more source

Congenital Malformations of the Eye: A Pictorial Review and Clinico‐Radiological Correlations

Journal of Ophthalmology, Volume 2024, Issue 1, 2024.
Congenital malformations of the eye represent a wide and heterogeneous spectrum of abnormalities that may be part of a complex syndrome or be isolated. Ocular malformation severity depends on the timing of the causative event during eye formation, ranging from the complete absence of the eye if injury occurs during the first weeks of gestation, to ...
Alessia Guarnera, Paola Valente, Luca Pasquini, Giulia Moltoni, Francesco Randisi, Chiara Carducci, Alessia Carboni, Giulia Lucignani, Antonio Napolitano, Antonino Romanzo, Daniela Longo, Carlo Gandolfo, Maria Camilla Rossi-Espagnet, Arturo Carta   +13 more
wiley   +1 more source

Scleral Fixation of Toric Intraocular Lens in the Absence of Capsular Support

Case Reports in Ophthalmological Medicine, Volume 2024, Issue 1, 2024.
The study is aimed at describing a technique for scleral fixation of toric intraocular lens (TIOL) in the eyes without capsular support coexisting with corneal astigmatism. A monofocal toric hydrophobic lens with eyelets at the optic‐haptic junction (enVista One‐Piece Hydrophobic Acrylic MX60T Toric IOL; Bausch & Lomb) was fixated to the sclera using ...
Karolina Krix-Jachym, Natalia Błagun, Marek Rękas, Kamal Kishore   +3 more
wiley   +1 more source

Choroidal neovascularization associated with coloboma of the choroid: A series of three cases

Indian Journal of Ophthalmology, 2011
Choroidal neovascularization (CNV) is a rare complication associated with coloboma of the choroid. We describe three cases of coloboma choroid where there was loss of vision due to CNV development at the edge of the coloboma.
Bhende Muna, Suganeswari G, Gopal Lingam, Bhende Pramod, Gopal Lekha, Rao Chetan   +5 more
doaj  

Identification of a candidate gene for astigmatism [PDF]

, 2013
PURPOSE. Astigmatism is a common refractive error that reduces vision, where the curvature and refractive power of the cornea in one meridian are less than those of the perpendicular axis. It is a complex trait likely to be influenced by both genetic and
Andrew, Toby, Cumberland, Phillippa, Hammond, Christopher J., Hewitt, Alex W., Hysi, Pirro G., Klaver, Caroline C. W., Lopes, Margarida C., Macgregor, Stuart, Mackey, David A., Montgomery, Grant W., Oostra, Ben, Rahi, Jugnoo S., Uitterlinden, Andre G., van Duijn, Cornelia M., Verhoeven, Virginie J. M., Vingerling, Johannes R., Young, Terri L.   +16 more
core   +1 more source

Expanding the Interface: Overlooked Dermatologic Disorders With Ocular Involvement

JEADV Clinical Practice, Volume 4, Issue 5, Page 1239-1243, December 2025.
A George
wiley   +1 more source

Active surveillance of visual impairment due to adverse drug reactions: findings from a national study in the United Kingdom [PDF]

, 2015
As visual impairment (VI) due to adverse drug reactions (ADR) is rare in adults and children, there is an incomplete evidence base to inform guidance for screening and for counseling patients on the potential risks of medications.
Cumberland, PM, Rahi, JS, Russell-Eggitt, I   +2 more
core  

Nonsyndromic bilateral and unilateral optic nerve aplasia: first familial occurrence and potential implication of CYP26A1 and CYP26C1 genes [PDF]

, 2011
Purpose: Optic nerve aplasia (ONA, OMIM 165550) is a very rare unilateral or bilateral condition that leads to blindness in the affected eye, and is usually associated with other ocular abnormalities.
Brachet, Cecile, Christophe, Catherine, De Baere, Elfride, Delpierre, Isabelle, Depasse, Fanny, Meire, Françoise, Menten, Björn, Roulez, Françoise, Van Nechel, Chrisitan   +8 more
core   +1 more source