Results 51 to 60 of about 9,846 (215)

Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]

open access: yes, 2020
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I   +3 more
core   +2 more sources

Prostate Cancer Detected by Choroidal Tumor and Complete Response to Hormonal Therapy: Case Report and Literature Review of 24 Patients With Choroidal Metastasis From Prostate Cancer

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2021
Metastatic choroidal tumors derived from prostate cancer are rare. In this study, we report a patient who manifested a choroidal tumor as the initial presenting sign of prostate cancer and review 23 patients with choroidal metastasis of prostate cancer ...
Toshihiko Matsuo MD, PhD   +3 more
doaj   +1 more source

Unilateral simultaneous optic nerve and choroidal infiltration – unusual presentation of metastatic disease in breast carcinoma

open access: yesGMS Ophthalmology Cases, 2021
Breast carcinoma metastasis can involve any ocular structures, but involvement of the optic nerve is extremely rare. Choroidal metastasis is usually multifocal as well as bilateral and occurs late.
Kumar, Poninder   +4 more
doaj   +1 more source

Presumed choroidal metastasis from soft tissue myoepithelial carcinoma [PDF]

open access: yes, 2019
Purpose: To report a case of presumed choroidal metastasis from soft tissue myoepithelial carcinoma and highlight challenges in its diagnosis. Observations: A 52-year-old man was referred with a two-week history of photopsia in his left eye.
Bonar, Fiona   +4 more
core   +1 more source

Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma [PDF]

open access: yes, 2016
The pediatric ocular tumor retinoblastoma readily metastasizes, but these lesions can masquerade as histologically similar pediatric small round blue cell tumors.
Argiropoulos, Bob   +11 more
core   +1 more source

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

open access: yesSmall, EarlyView.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito   +2 more
wiley   +1 more source

Multimodal Imaging in Diagnosis of Choroidal Metastasis in Breast Carcinoma

open access: yesDelhi Journal of Ophthalmology, 2021
Intraocular metastasis is the most common malignancy of the eye in adults. It is commonly noted in uveal tract with choroid being the most common site due to its high vascularity.
Sriram Simakurthy   +5 more
doaj   +1 more source

Primary photodynamic therapy with verteporfin for pigmented posterior pole cT1a choroidal melanoma: a 3-year retrospective analysis [PDF]

open access: yes, 2018
AIMS: To investigate the outcomes of primary photodynamic therapy (PDT) for pigmented posterior pole cT1a choroidal melanoma. METHODS: Retrospective interventional consecutive case series of 26 patients (26 eyes) with pigmented posterior pole cT1a ...
Arora, AK   +5 more
core   +1 more source

Long‐Term Local Control and Mortality After Transpupillary Thermotherapy of Small Uveal Melanomas

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Transpupillary thermotherapy (TTT) is used for selected small choroidal melanocytic tumours, either as primary treatment or as an adjunct to plaque brachytherapy. We compared long‐term local recurrence and mortality outcomes after primary TTT alone, plaque brachytherapy combined with TTT (brachy+TTT), and plaque brachytherapy alone (
Maria Fili   +5 more
wiley   +1 more source

Heterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma. [PDF]

open access: yes, 2013
PurposeTo report on the heterogeneity of monosomy 3 in a fine needle aspiration biopsy obtained transsclerally from choroidal melanoma for prognosis.MethodsAll clinical records for patients who had been diagnosed with choroidal melanoma and underwent ...
Burgess, Barry L   +4 more
core   +2 more sources

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