Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I +3 more
core +2 more sources
Metastatic choroidal tumors derived from prostate cancer are rare. In this study, we report a patient who manifested a choroidal tumor as the initial presenting sign of prostate cancer and review 23 patients with choroidal metastasis of prostate cancer ...
Toshihiko Matsuo MD, PhD +3 more
doaj +1 more source
Breast carcinoma metastasis can involve any ocular structures, but involvement of the optic nerve is extremely rare. Choroidal metastasis is usually multifocal as well as bilateral and occurs late.
Kumar, Poninder +4 more
doaj +1 more source
Presumed choroidal metastasis from soft tissue myoepithelial carcinoma [PDF]
Purpose: To report a case of presumed choroidal metastasis from soft tissue myoepithelial carcinoma and highlight challenges in its diagnosis. Observations: A 52-year-old man was referred with a two-week history of photopsia in his left eye.
Bonar, Fiona +4 more
core +1 more source
Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma [PDF]
The pediatric ocular tumor retinoblastoma readily metastasizes, but these lesions can masquerade as histologically similar pediatric small round blue cell tumors.
Argiropoulos, Bob +11 more
core +1 more source
Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito +2 more
wiley +1 more source
Multimodal Imaging in Diagnosis of Choroidal Metastasis in Breast Carcinoma
Intraocular metastasis is the most common malignancy of the eye in adults. It is commonly noted in uveal tract with choroid being the most common site due to its high vascularity.
Sriram Simakurthy +5 more
doaj +1 more source
Primary photodynamic therapy with verteporfin for pigmented posterior pole cT1a choroidal melanoma: a 3-year retrospective analysis [PDF]
AIMS: To investigate the outcomes of primary photodynamic therapy (PDT) for pigmented posterior pole cT1a choroidal melanoma. METHODS: Retrospective interventional consecutive case series of 26 patients (26 eyes) with pigmented posterior pole cT1a ...
Arora, AK +5 more
core +1 more source
Long‐Term Local Control and Mortality After Transpupillary Thermotherapy of Small Uveal Melanomas
ABSTRACT Background Transpupillary thermotherapy (TTT) is used for selected small choroidal melanocytic tumours, either as primary treatment or as an adjunct to plaque brachytherapy. We compared long‐term local recurrence and mortality outcomes after primary TTT alone, plaque brachytherapy combined with TTT (brachy+TTT), and plaque brachytherapy alone (
Maria Fili +5 more
wiley +1 more source
Heterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma. [PDF]
PurposeTo report on the heterogeneity of monosomy 3 in a fine needle aspiration biopsy obtained transsclerally from choroidal melanoma for prognosis.MethodsAll clinical records for patients who had been diagnosed with choroidal melanoma and underwent ...
Burgess, Barry L +4 more
core +2 more sources

