Results 81 to 90 of about 9,846 (215)

Experiences of two different modalities in the management of choroidal melanoma in the Asian Indian population

South Asian Journal of Cancer, 2017
Background: Choroidal malignant melanoma is a rare intraocular cancer in Asian Indian population. There is a paucity of data from our population comparing iodine 125 (I-125) brachytherapy and enucleation.
Prajna Meeralakshmi, Parag K Shah, Venkatapathy Narendran   +2 more
doaj   +1 more source

Photofrin II as an efficient radiosensitizing agent in an experimental tumor [PDF]

, 2001
Background and Objective: The use of ionizing irradiation as radiation therapy (RT) for tumor treatment represents a well-established method. The use of photodynamic therapy (PDT), especially with Photofrin II, for tumor treatment is also known. Chemical
Corti, L., Dühmke, Eckhart, Hofstetter, Alfons, Jori, G., Schaffer, Moshe, Schaffer, Pamela Manuela, Sotti, G.   +6 more
core   +1 more source

Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment

SmartMat, Volume 7, Issue 1, February 2026.
Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova, Ioannis Iliadis, Malamati Poimenidou, Chrysi Patsidou, Maria Zafeiriou‐Chatziefraimidou, Diamantis D. Almaliotis, Ioannis T. Tsinopoulos, Ivan V. Zelepukin, Alexey V. Yaremenko   +8 more
wiley   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Choroidal metastasis as initial presentation of squamous cell carcinoma lung in a patient who had undergone treatment for carcinoma hypopharynx [PDF]

Journal of Clinical and Scientific Research, 2016
Choroidal metastasis is the most common intraocular malignancy followed by ocular melanoma. This presentation is reported commonly in breast and lung malignancies with multifocal involvement of one eye, or involvement of both eyes.
Prathipati A, Jilla S, Sandhya CS, Vijaya Lakshmi B, Narayan ML, Rukmangadha N   +5 more
doaj   +1 more source

Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]

, 2019
Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana, Conway, Robert Max, Gratton, Enrico, Macmillan, Alexander, Madigan, Michele C, Sitiwin, Ephrem, Whan, Renee   +6 more
core  

Beyond Treatment: The Strategy of Nonintervention in Choroidal Hemangioma

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT The circumscribed choroidal hemangioma (CCH) is a benign congenital eye tumor whose etiology is not clear. A 41‐year‐old female patient came with a 2‐year history of slowly progressive deteriorating vision in her right eye. In the left eye, the best‐corrected visual acuity (BCVA) was 6/6, and counting fingers at 1 m in the right eye.
Humdan Khan, Muhammad Shaheer Bin Faheem, Hurmat Fatima, Asfandyar Asghar, Ahmed Ali Khan, Muhammad Rehan Zahid, Syed Tawassul Hassan, Izzah Shakkel, Muhammad Idrees Khan   +8 more
wiley   +1 more source

Cytogenetic analysis of uveal melanomas: a long-term experience [PDF]

, 2013
Background/aim: Cytogenetic profile of posterior uveal melanoma (mainly monosomy 3) is actually considered the most specific prognostic factor for uveal melanoma patients.
Parrozzani, Raffaele
core   +1 more source

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models. [PDF]

, 2017
Melanoma is a recalcitrant disease. Melanoma patients with the BRAF-V600E mutation have been treated with the drug vemurafenib (VEM) which targets this mutation.
Chmielowski, Bartosz, Dry, Sarah M, Eilber, Fritz C, Han, Qinghong, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Shukuan, Li, Yunfeng, Miyake, Kentaro, Miyake, Masuyo, Murakami, Takashi, Nelson, Scott D, Russell, Tara A, Tan, Yuying, Unno, Michiaki   +16 more
core   +1 more source

Tumor Habitats Based on Multiparametric MRI Distinguish Atypical Glioblastoma From Primary Central Nervous System Lymphoma: Imaging‐Pathologic Correlation

Journal of Magnetic Resonance Imaging, Volume 63, Issue 1, Page 142-154, January 2026.
ABSTRACT Background Atypical glioblastoma (GBM) (minimal or no necrosis on MRI) and primary central nervous system lymphoma (PCNSL) are difficult to distinguish on MRI; whether tumor habitat can more accurately distinguish atypical GBM from PCNSL remains uncertain.
Meng‐nan Sun, Hui Wang, Yan‐ying Yang, Xiao‐jun Yu, Hai‐nan Li, Dan‐dan Fu, Dong‐Zhang, Ru‐yu Ai, Xiao‐yu Hua, Li‐chao Wang, Ming‐yao Lai, Chang‐zheng Shi, Lin‐bo Cai   +12 more
wiley   +1 more source