Results 21 to 30 of about 35,691 (227)

Complement C3 variant and the risk of age-related macular degeneration [PDF]

open access: yes, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM   +16 more
core   +1 more source

Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization.

open access: yesPLoS ONE, 2017
This study investigated the potential role of sirtuin 1 in Müller glial cells in choroidal neovascularization. In the in vitro study, primary Müller glial cells were cultured and treated with resveratrol, a sirtuin 1 activator.
Tomoka Ishida   +6 more
doaj   +1 more source

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]

open access: yes, 2019
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core   +1 more source

An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management

open access: yesJournal of Ophthalmic Inflammation and Infection, 2018
Inflammatory choroidal neovascular membranes are challenging to diagnose and manage. A number of uveitic entities may be complicated by the development of choroidal neovascularization leading to a decrease in central visual acuity.
Aniruddha Agarwal   +8 more
doaj   +1 more source

Adverse events associated with intraocular injection of anti-VEGF(bevacizumab) in retinal vein ccclusion: a case report [PDF]

open access: yes, 2015
Introduction: Antiangiogenic agents are often administered for treatment of Branch Retinal Vein Occlusion (BRVO). Among them, Bevacizumab has noticeable antiangiogenic and antiedemigenic properties and possesses great capacity to penetrate the retinal ...
ARTICO, Marco   +7 more
core   +1 more source

OCT angiography for the diagnosis and management of choroidal neovascularization secondary to choroideremia

open access: yesAmerican Journal of Ophthalmology Case Reports, 2021
Purpose: To describe the multimodal imaging findings and treatment outcomes in choroidal neovascularization secondary to Choroideremia. Observations: A 13-year-old male presented with reduced visual acuity in the left eye. He gave a history of nyctalopia.
Ratnesh Ranjan   +5 more
doaj   +1 more source

Concurrent management of myopic choroidal neovascularization and rhegmatogenous retinal detachment with intravitreal antivascular endothelial growth factor during primary retinal detachment repair

open access: yesIndian Journal of Ophthalmology, 2018
We report concurrent management of rhegmatogenous retinal detachment and myopic choroidal neovascularization in the left eye of a 24-year-old female who presented with sudden dimness of vision due to retinal detachment and choroidal neovascularization ...
Kumar Saurabh   +3 more
doaj   +1 more source

Reduced Retinal Microvascular Density, Improved Forepaw Reach, Comparative Microarray and Gene Set Enrichment Analysis with c-jun Targeting DNA Enzyme [PDF]

open access: yes, 2015
Retinal neovascularization is a critical component in the pathogenesis of common ocular disorders that cause blindness, and treatment options are limited.
Chan, Cecilia W. S   +3 more
core   +1 more source

Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration. [PDF]

open access: yes, 2011
International audienceThe pro-inflammatory cytokine IL-1β has been shown to promote angiogenesis. It can have a neurotoxic or neuroprotective effect. Here, we have studied the expression of IL-1β in vivo and the effect of the IL-1 receptor antagonist on ...
Behar-Cohen, Francine   +11 more
core   +5 more sources

Jugular Vein Insufficiency and Choroidal Neovascularization in Moderate Myopia: A New Unknown Factor of Additional Risk?

open access: yesCase Reports in Ophthalmological Medicine, 2015
To date, choroidal blood flow reduction in highly myopic eyes appears to be related to the development of choroidal neovascularization secondary to local reduction of arterial flow.
Massimiliano Farina   +2 more
doaj   +1 more source

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