Results 111 to 120 of about 2,800 (230)

Peripapillary Choroidal Vascularity Index and Microstructure of Parapapillary Atrophy

Investigative Opthalmology & Visual Science, 2019
To investigate the association between the microstructure of β-zone parapapillary atrophy (βPPA) and choroidal vascularity index (CVI) determined by spectral-domain optical coherence tomography (SD-OCT) in glaucomatous eyes.A total of 160 eyes of 160 primary open-angle glaucoma patients with βPPA were included. Total choroidal area (TCA), luminal area (
Min Hee, Suh, Jun Woo, Park, Neha, Khandelwal, Rupesh, Agrawal   +3 more
openaire   +2 more sources

Synergistic inhibition of macular vascular permeability in diabetic edema: Ginsenoside Rg3 enhances ranibizumab efficacy by targeting angiopoietin‐like protein 4 and vascular endothelial growth factor via neuropilin/RhoA signaling

Journal of Diabetes Investigation, EarlyView.
Molecular mechanism of synergistic antagonism of ANGPTL4 and VEGF by ginsenoside Rg3 combined with ranibizumab, regulating the NRP/RhoA pathway to inhibit macular edema. ABSTRACT Aims This study investigated the molecular mechanisms by which ginsenoside Rg3 combined with ranibizumab alleviates diabetic macular edema (DME), focusing on antagonizing ...
Jiexin Yu, Xingyu Li, Yanli Liu
wiley   +1 more source

Choroidal remodeling following different anti-VEGF therapies in neovascular AMD

Scientific Reports
The purpose of this study was to investigate choroidal morphology remodeling in AMD-associated type 1 macular neovascularization using two different anti-VEGF drugs.
Giacomo Boscia, Nikolai Pozharitskiy, Maria Oliva Grassi, Enrico Borrelli, Marina D’Addario, Giovanni Alessio, Francesco Boscia, Pasquale Viggiano   +7 more
doaj   +1 more source

Choroidal vascular changes in internal carotid artery stenosis: a retrospective cohort study in Chinese population

BMC Ophthalmology, 2019
Background To evaluate choroidal vascularity index (CVI) in eyes with internal carotid artery (ICA) stenosis using binarization tool in enhanced depth images scanned by spectral domain optical coherence tomography.
Shuang Li, Xuqiang Lang, Wei Wang, Yang Yang, Jingjing Wang, Hongyang Li, Yanling Wang, Kang Wang   +7 more
doaj   +1 more source

Choroidal biomarkers in age-related macular degeneration [PDF]

Age-related macular degeneration (AMD) is the leading cause of central visual impairment in the elderly. The exact pathophysiological mechanisms for AMD remain uncertain.
Baek J., Chhablani J., Ejlalidiz M., Hasan N., Iannetta D., Ibrahim M. N., Rahmanipour E., Rasheed M. A., Sadeghi E., Valsecchi N., Vupparaboina K. K.   +10 more
core   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Effects of metformin on retinoblastoma growth in vitro and in vivo [PDF]

, 2014
Recent studies suggest that the anti-diabetic drug metformin may reduce the risk of cancer and have anti-proliferative effects for some but not all cancers. In this study, we examined the effects of metformin on human retinoblastoma cell proliferation in
BRODOWSKA, KATARZYNA, CICHY, JOANNA, GRAGOUDAS, EVANGELOS S., HOANG, MIEN, HÖRSTE, MELISSA MEYER ZU, KIERNAN, ELIZABETH, MILLER, JOAN W., PASCHALIS, ELEFTHERIOS I., RAMSEY, DAVID J., SCOTT, GORDON, TAKEUCHI, KIMIO, THEODOROPOULOU, SOFIA, VAVVAS, DEMETRIOS G.   +12 more
core   +2 more sources

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Choroidal Vascularity Index (CVI)--A Novel Optical Coherence Tomography Parameter for Monitoring Patients with Panuveitis?

PLoS ONE, 2016
PurposeTo compute choroidal vascularity index (CVI) using an image binarization tool on enhanced depth imaging (EDI)-optical coherence tomography (OCT) scans as a non-invasive optical tool to monitor progression in panuveitis and to investigate the ...
Rupesh Agrawal, Mohammed Salman, Kara-Anne Tan, Michael Karampelas, Dawn A Sim, Pearse A Keane, Carlos Pavesio   +6 more
doaj   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source