Results 121 to 130 of about 2,800 (230)

A computational model for retinal haemodynamics under gravitational and postural variations

The Journal of Physiology, EarlyView.
Abstract figure legend The haemodynamic impact of gravitational and postural changes on the retina, and its relevance to spaceflight associated neuro‐ocular syndrome (SANS), remains incompletely characterized. This study assesses retinal haemodynamics from upright to head‐down tilt using a lumped‐parameter model that dynamically couples intraocular ...
Michele Nigro, Andrea Montanino, Eduardo Soudah   +2 more
wiley   +1 more source

Choroidal vascularity index in eyes with central macular atrophy secondary to age-related macular degeneration and Stargardt disease [PDF]

, 2022
Borrelli, E.
core   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, Volume 30, Issue 2, Page 168-175, April 2026.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
The role of 42 amino acids long amyloid beta (Aβ) in the retinal pigment epithelium (RPE) was investigated using 5xFAD mice model overproducing Aβ. The RPE cells of 5xFAD mice showed increased oxidative stress, accumulation of autophagy‐destined proteins, increased expression of secretory autophagy markers, and increase in epithelial‐to‐mesenchymal ...
Johanna Ruuth, Toni Tamminen, Elisa Toropainen, Heikki Tanila, Juha M. T. Hyttinen, Tarja Malm, Kai Kaarniranta, Ali Koskela   +7 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Comparison of choroidal structural changes between term and preterm children with and without retinopathy of prematurity

Photodiagnosis and Photodynamic Therapy
Purpose: To evaluate the effects of prematurity and retinopathy of prematurity (ROP) treatment on choroidal structure using the image binarization method and compare with term children.
Oğuzhan Oruz, Mehmet Serdar Dervişoğulları   +1 more
doaj   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, Volume 13, Issue 16, 18 March 2026.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

Dual‐Target ROS‐Driven Spatiotemporal Senolysis for Vascular Repair and Immune Microenvironment Reprogramming in the Treatment of Ocular Fundus Neovascularization

Advanced Science, Volume 13, Issue 16, 18 March 2026.
We developed a senolytic approach using procyanidin C1 (PCC1)‐loaded platform, a clinically established and safe hyaluronic acid‐based scaffold, to selectively eliminate senescent endothelial and microglial cells. This dual‐targeting strategy significantly suppresses pathological neovascularization and promotes vascular repair, presenting a safe and ...
Yali Zhou, Tianxing Chen, Peiyu Liu, Kangjia Lv, Yifan Wang, Xiaoqian Wang, Junwei Fang, Chong Chen, Zhaoyang Wang, Fang Wei, Xun Xu   +10 more
wiley   +1 more source

Evaluation of Cerebral Blood Flow and Cerebral Autoregulation Using Synthetic Data and In Silico Modeling

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
This study uses simulations and synthetic data to reassess static cerebral autoregulation. Results show cerebral blood flow is strongly influenced by systemic arteriolar resistance and arterial CO2, while mean arterial pressure has a significant but weak effect.
Selim Bozkurt
wiley   +1 more source

Healthy Dietary Patterns and Risk of Major Eye Diseases: Evidence From Nationally Population‐Based Data and Bibliometric Analysis

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study found that higher adherence to HEI‐2020, DASH, and Mediterranean dietary patterns was associated with a lower prevalence of selected major eye diseases. ABSTRACT The associations between dietary patterns and major eye diseases remain incompletely understood.
Kunhong Xiao, Jiajia Gao, Yiyan Zhang, Ruiye Chen, Yuqing Wang, Chufeng Gu, Jiahao Liu, Yan Huang, Li Li   +8 more
wiley   +1 more source