Results 41 to 50 of about 390,033 (246)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Collective Wisdom and Practical Knowledge: the New Christian Journal for Global Health
The Christian Journal for Global Health is an initiative of the Center for Health in Mission. It reflects a broad and expanding collaborative movement involving a large number of individuals and organizations globally.
doaj +1 more source
Building Religious Harmony Among Young Children: Experience from Indonesian Elementary School
This article is a study of the harmonization of Islam, Christianity, and Buddhism in SD Negeri (State Elementary School) 46 Hulontalangi, Gorontalo City.
Djunawir Syafar, Mujahid Damopolii
doaj +1 more source
The mission of the church in the Romanian cultural space [PDF]
Church life is part of the life of our people, who were born Christian; therefore, we cannot consider that what has been said about the Christianity of our great poet Mihai Eminescu, about his views of the ancestral Church, the oldest institution of this
Bogdan MOHOR OBREJA
doaj
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
A Study of John 21:15-17: Toward a Shepherd Model of Christian Ministry
Leadership is one of the key challenges facing the contemporary society despite many seminars, conferences and workshops organized on this subject. The political crises in many organizations and societies are the result of poor leadership. The subject of
Isaac Boaheng, Isaac Justice Osei
doaj +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source

