Results 61 to 70 of about 59,524 (243)
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
Advanced Science, EarlyView.High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao +11 more
wiley +1 more source
How to Amend Christian List’s Theory on Free Will to Answer the Challenge from Indeterminism
, 2023 Christian List describes his position on free will as compatibilist libertarianism, meaning that free will in his view is compatible with determinism on the ultimate physical level of description, but it fulfils the libertarian requirement of alternative possibilities by having indeterminism on a higher psychological or intentional level. I argue that,
openaire +1 more source
Advanced Science, EarlyView.Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.A non‐destructive, quantitative approach has been developed to explore the nanoscale dynamics of TaOx‐based memristive devices. The utilization of nano‐X‐ray fluorescence analysis enables the direct probing of spatially resolved elemental distributions, including those present in buried layers, that are critical for the resistive switching.
André Wählisch +9 more
wiley +1 more source
A Large Scale Multi‐Modal Workflow for Battery Characterization: From Concept to Implementation
Advanced Energy Materials, EarlyView.Isolated characterization techniques produce independent datasets and single‐property insights. However, progressively more holistic interpretations of battery‐material behavior is needed in the future. Here we demonstrate a coordinated multimodal workflow enabling the correlation of heterogeneous datasets and the construction of multidimensional ...
François Cadiou +34 more
wiley +1 more source
The Problem of the First Belief: Group Agents and Responsibility
Journal of Social Ontology, 2022 Attributing moral responsibility to an agent requires that the agent is a capable member of a moral community. Capable members of a moral community are often thought of as moral reasoners (or moral persons) and, thus, to attribute moral responsibility ...
Onni Hirvonen
doaj
Gas migration and slope instability in the Danube Fan: insights from integrated OBS-MCS seismic analysis [PDF]
Solid EarthGas hydrates and deltaic deep-sea fans are main features in continental margin systems, influencing slope stability, fluid migration, and carbon cycling.
H.-S. Hilbert +8 more
doaj +1 more source
Agribusiness, EarlyView.ABSTRACT Despite the broad focus on necessity‐ and opportunity‐driven entrepreneurship in research and policy, the entrepreneurial dichotomy within the agribusiness context has not been adequately addressed. This study contributes to closing this knowledge gap by examining youth's perceptions of agribusiness through the lens of the push‐pull motivation
Cool Dady Mangole +6 more
wiley +1 more source
Predictive power demand for energy management of hybrid electric tractors
Smart Agricultural TechnologyStricter emission regulations are driving the electrification of agricultural and equipment machinery, including tractors. In order to enable predictive energy management strategies aimed at reducing fuel consumption and carbon emissions, this study ...
Christian Varlese +5 more
doaj +1 more source