Results 21 to 30 of about 18,774 (259)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
BEYOND RELATIVISM AND FOUNDATIONALISM: A PROLEGOMENON TO FUTURE RESEARCH IN ETHICS
Zygon, 1994 . This article examines the similarities between notions about the nature of reality held by some Christian mystics (Thomas Merton and the author of The Cloud of Unknowing) and those proposed by physicists David Bohm and Henry Margenau.
doaj +2 more sources
Pastoral Therapy on Euthanasia: Christian Humanism and Ubuntu Embracing Openness [PDF]
Pharos Journal of TheologyThe debate over practices of physician-assisted suicide, euthanasia and other end-of-life questions is still ongoing in many countries around the world.
Dr. Mmamajoro Phalatsi-Shilubana
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto +12 more
wiley +1 more source
Osoba Jezusa Chrystusa istotą eschatologii chrześcijańskiej
Studia Koszalińsko-Kołobrzeskie, 2015 The aim of the article The Christian teaching and practice in anticipation of Parusia is to show the most important elements of Christian eschatology in a context of errors like millenarism or setting the exact date of the end of the world.
Janusz Bujak
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein +7 more
wiley +1 more source
“Live a Life of Experience”: A Methodological Proposal by Luigi Giussani
Богословські роздуми: Східноєвропейський журнал богословʼя, 2018 The article explores the category of experience as it is proposed by Italian priest and pedagogist Luigi Giussani (1922-2005). The author analyses why and how L. Giussani took an interest in this category, and shows the methodological peculiarity of his
Mikhail FADZEYEU
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi +10 more
wiley +1 more source