Results 271 to 280 of about 637,735 (407)

Microtracer‐Based Assessment of the Mass Balance, Pharmacokinetics, and Excretion of [14C]Berzosertib, an Intravenous ATR Inhibitor, in Patients With Advanced Solid Tumors: A Phase 1 Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Berzosertib is a small‐molecule ataxia telangiectasia and Rad3‐related protein inhibitor. To assess the clearance mechanism(s) of berzosertib, a Phase 1, 2‐period, open‐label study was conducted in adults with advanced solid tumors who were treated with a single intravenous dose of 210 mg/m2 berzosertib containing approximately 3 µCi of [14C ...
Jayaprakasam Bolleddula   +12 more
wiley   +1 more source

Spin‐Crossover in a Dinuclear Iron(II) Complex on Highly Oriented Pyrolytic Graphite: An X‐Ray Absorption Spectroscopy Study

open access: yesChemPhysChem, EarlyView.
This study investigates a spin‐crossover dinuclear Fe(II) complex deposited as a thin film under ultrahigh‐vacuum conditions by a pulsed layer injection technique. Its temperature‐dependent switching behavior, light‐induced excited spin‐state trapping, soft‐X‐ray‐induced excited spin‐state trapping, and temperature‐ and light‐induced spin crossover ...
Marcel Walter   +12 more
wiley   +1 more source

Surface Deposition of Dome‐Shaped Metal‐Organic Complexes: A New Approach to the Generation of Single‐Site Catalysts

open access: yesChemPlusChem, EarlyView.
This study describes the synthesis of a new dithia‐[2.1.1]‐(2,6)‐pyridinophane ligand and its molybdenum(0) tricarbonyl complex. Monolayers of the dome‐shaped complex on Au(111) are investigated by employing surface spectroscopic methods (infrared reflection absorption spectroscopy, X‐ray photoelectron spectroscopy, near‐edge X‐ray absorption fine ...
Küpra Yildiz   +4 more
wiley   +1 more source

Symmetric Bis‐Kryptopyrrol‐2‐Yl Squaraine as a Viscosity Probe and Dual‐State Emitter

open access: yesChemPhotoChem, EarlyView.
Previously unknown capabilities of one of the original squaraine dyes as a viscosity probe and dual‐state emitter are revealed, with aggregated forms of the dye being responsible for the near‐IR emission in the solid state. Easily accessible small organic fluorophores with multiplexing capabilities are of interest for a variety of fields.
Daniel D. Ta   +15 more
wiley   +1 more source

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