The antimicrobial peptides secreted by the chromaffin cells of the adrenal medulla link the neuroendocrine and immune systems: From basic to clinical studies [PDF]
Frontiers in Immunology, 2022 The increasing resistance to antibiotic treatments highlights the need for the development of new antimicrobial agents. Antimicrobial peptides (AMPs) have been studied to be used in clinical settings for the treatment of infections.
Francesco Scavello +9 more
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Intrinsic GABAergic system of adrenal chromaffin cells. [PDF]
Proceedings of the National Academy of Sciences, 1984 Histochemical and biochemical studies demonstrate that gamma-aminobutyric acid (GABA), glutamic acid decarboxylase (EC 4.1.1.15), and GABA aminotransferase (EC 2.6.1.19) are present in bovine adrenal chromaffin cells. Moreover, [3H]GABA can be taken up and stored by primary cultures of adrenal chromaffin cells.
Y, Kataoka +7 more
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To the study of the chromaffin system
Kazan medical journal, 1915 According to my general plan to examine the organs of the chromaffin system, after a description of the additional organs of the sympathetic nerve-typical chromaffin formations, followed by a description of the carotid gland, where chromaffin elements are built only separately, I should have touched the structure and the so-called coccyx gland in man ...
N. M. Yakhontov
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A Defined, Controlled Culture System for Primary Bovine Chromaffin Progenitors Reveals Novel Biomarkers and Modulators [PDF]
Stem Cells Translational Medicine, 2014 Abstract We present a method to efficiently culture primary chromaffin progenitors from the adult bovine adrenal medulla in a defined, serum-free monolayer system. Tissue is dissociated and plated for expansion under support by the mitogen basic fibroblast growth factor (bFGF). The cultures, although
Jimmy, Masjkur +11 more
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Molecular mechanisms of exocytosis: The adrenal chromaffin cell as a model system
Cellular and Molecular Neurobiology, 1988 1. The release of neurotransmitters, hormones, and enzymes involves exquisitely regulated events which ultimately result in the fusion of the secretory vesicle with the cell's plasma membrane, releasing the vesicle contents into the extracellular space. 2.
Warren J. Strittmatter
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A rare case of non-functional Paraganglioma of urinary bladder with No LUTS [PDF]
Urology Case ReportsParaganglioma originates from chromaffin cells of the sympathetic nervous system. Paraganglioma of urinary bladder are very rare tumors that arise from the ganglion cells and usually mistakenly have been diagnosed and treated because of its rarity and ...
Mohammad Poury +3 more
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Biomedicines, 2022 A reliable prediction of the recurrence risk of pheochromocytoma after radical surgery would be a key element for the tailoring/personalization of post-surgical follow-up.
Mirko Parasiliti-Caprino +19 more
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Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells
iScience, 2021 Summary: The intestinal microbiota closely interacts with the neuroendocrine system and exerts profound effects on host physiology. Here, we report that nucleotide-binding oligomerization domain 1 (Nod1) ligand derived from intestinal bacteria modulates ...
Chen Xiang +7 more
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Membrane toxicity of abnormal prion protein in adrenal chromaffin cells of scrapie infected sheep. [PDF]
PLoS ONE, 2013 Transmissible spongiform encephalopathies (TSEs) or prion diseases are associated with accumulations of disease specific PrP (PrP(d)) in the central nervous system (CNS) and often the lymphoreticular system (LRS).
Gillian McGovern, Martin Jeffrey
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Differentiation in neuroblastoma: diffusion-limited hypoxia induces neuro-endocrine secretory protein 55 and other markers of a chromaffin phenotype. [PDF]
PLoS ONE, 2010 Neuroblastoma is a childhood malignancy of sympathetic embryonal origin. A high potential for differentiation is a hallmark of neuroblastoma cells. We have previously presented data to suggest that in situ differentiation in tumors frequently proceeds ...
Fredrik Hedborg +5 more
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