Results 61 to 70 of about 15,801 (196)

Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels

Marine Drugs, 2017
Voltage-gated calcium (CaV) channels are widely expressed and are essential for the completion of multiple physiological processes. Close regulation of their activity by specific inhibitors and agonists become fundamental to understand their role in ...
David Ramírez, Wendy Gonzalez, Rafael A. Fissore, Ingrid Carvacho   +3 more
doaj   +1 more source

Long-term follow-up after en bloc resection and reconstruction of a solitary paraganglioma metastasis in the first lumbar vertebral body: a case report

Journal of Medical Case Reports, 2011
Introduction Paragangliomas are rare tumors that originate from the autonomic nervous system-associated paraganglia. They metastasize infrequently. Malignancy can only be demonstrated by the presence of chromaffin tissue at sites where it usually is not ...
Liljenqvist Ulf R, Lerner Thomas, Halm Henry F, Richter Alexander, Quante Markus   +4 more
doaj   +1 more source

Kidneys and adrenal glands of Caiman yacare (Daudin, 1802) (Crocodylia: Alligatoridae): morphology and morphometry [PDF]

Anais da Academia Brasileira de Ciências
Crocodilians are semi-aquatic reptiles with highly sophisticated anatomy and physiology that are well adapted to dwell in freshwater environments or be exposed to brackish and saltwater, indicating the complex nature of the organization and function of ...
MARIANA O. LIMA, LEONARDO L. GORZA, EDUARDO JOSÉ S. BORGES, YHURI C. NÓBREGA, LEONARDO O. TRIVILIN, RODRIGO G. FIGUEIREDO, MARIA APARECIDA DA SILVA   +6 more
doaj   +1 more source

The human channel gating–modifying A749G CACNA1D (Cav1.3) variant induces a neurodevelopmental syndrome–like phenotype in mice

JCI Insight, 2023
Germline de novo missense variants of the CACNA1D gene, encoding the pore-forming α1 subunit of Cav1.3 L-type Ca2+ channels (LTCCs), have been found in patients with neurodevelopmental and endocrine dysfunction, but their disease-causing potential is ...
Nadine J. Ortner, Anupam Sah, Enrica Paradiso, Josef Shin, Strahinja Stojanovic, Niklas Hammer, Maria Haritonova, Nadja T. Hofer, Andrea Marcantoni, Laura Guarina, Petronel Tuluc, Tamara Theiner, Florian Pitterl, Karl Ebner, Herbert Oberacher, Emilio Carbone, Nadia Stefanova, Francesco Ferraguti, Nicolas Singewald, Jochen Roeper, Jörg Striessnig   +20 more
doaj   +1 more source

PROTEOMIC INVESTIGATION OF PROTEOLYTIC SYSTEMS IN REGULATED SECRETORY VESICLES OF NEUROENDOCRINE CHROMAFFIN CELLS.

The FASEB Journal, 2006
Proprotein processing within regulated secretory vesicles is required for the production of biologically active peptides. In this study, investigation of the proteome of regulated secretory vesicles was performed to identify new protease and protease inhibitor components of these vesicles.
Jill Lee Wegrzyn, Vivian Hook, John Neveu, William Lane   +3 more
openaire   +1 more source

Bilateral pheochromocytoma: report of a patient

Acta Médica del Centro, 2013
Pheochromocytomas are sympathetic nervous system tumors that develop from the chromaffin cells and which are characterized by excessive production of catecholamines.
María Lourdes Sáez Gómez, Paula Carolina Aguila Soto, Anabet Santiago Pérez   +2 more
doaj  

Pheochromocytomas and Paragangliomas Diagnosis and Treatment

Revista Finlay, 2021
Pheochromocytomas and paragangliomas are catecholamine-producing neuroendocrine tumors from the sympathetic or parasympathetic nervous system. They originate in the chromaffin cells of the adrenal medulla and the extra-adrenal sympathetic ganglia.
Jorge Luis Soriano Lorenzo
doaj  

Chromogranin A regulates neuroblastoma proliferation and phenotype

Biology Open, 2019
Neuroblastoma is a commonly encountered solid tumor in early childhood with high neuroplasticity, and differentiation therapy is hypothesized to lead to tumor mass shrinkage and/or symptom relief.
Dongyun Zhang, Lilit Babayan, Hillary Ho, Anthony P. Heaney   +3 more
doaj   +1 more source

Cyclic Adenosine Monophosphate in Cardiac and Sympathoadrenal GLP-1 Receptor Signaling: Focus on Anti-Inflammatory Effects

Pharmaceutics
Glucagon-like peptide-1 (GLP-1) is a multifunctional incretin hormone with various physiological effects beyond its well-characterized effect of stimulating glucose-dependent insulin secretion in the pancreas. An emerging role for GLP-1 and its receptor,
Anastasios Lymperopoulos, Jordana I. Borges, Renee A. Stoicovy   +2 more
doaj   +1 more source

Clinical Evaluation, Diagnosis and Treatment of Pheochromocytoma

Acta Clinica Croatica
Pheochromocytomas are rare neuroendocrine tumors that originate in chromaffin cells of the adrenal medulla and excessively secrete catecholamines, which leads to a multitude of different symptoms.
Romana Marušić, Tajana Turk, Tatjana Bačun   +2 more
doaj   +1 more source