Results 101 to 110 of about 234,926 (314)

Determination of residual solvents in synthetic intermediate of Selexipag by headspace gas chromatograhy

open access: yesJournal of Hebei University of Science and Technology, 2019
In order to better control the quality of Selexipag products and ensure drug safety,headspace gas chromatography is established to detect the amount of solvent remaining in the synthesis of Selexipag intermediates 4-\ pyrazin -2-yl) (isopropyl) amino\]-1-
Haijuan QI   +5 more
doaj   +1 more source

Chromatographic Analysis of Eucalypt Kinos [PDF]

open access: yesNature, 1950
KINOS are dark cellular accretions or astringent exudations containing phenolic substances. They are commonly seen as vitreous lumps on the bark, or as veins in the timber, of many eucalypts, and are locally known as ‘gums’. The kinos of certain eucalypts have been examined by the Williams and Kirby's solvent ascent modification1 of the paper partition
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Analysis of Nucleosides and Nucleotides in Milk and Infant Formula [PDF]

open access: yes, 2013
Nucleotides have been routinely supplemented to infant formulas due to the important roles they play in metabolism and to replicate the higher concentrations typically found in human milk.
Gill, Brendon D.
core  

Analytical approaches and preparation of biological, food and environmental samples for analyses of zearalenone and its metabolites

open access: yesReviews in Analytical Chemistry, 2020
Zearalenone (ZEN) is a mycotoxin that occurs in all stages of plant growth and development and exerts harmful effects on humans and animals. Zearalenone is easily absorbed in the digestive tract, and it is metabolized in the intestinal wall and the liver.
Gadzała-Kopciuch Renata   +2 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Chromatographic Analysis of Olopatadine in Hydrophilic Interaction Liquid Chromatography [PDF]

open access: yes, 2015
In this paper, chromatographic analysis of active substance olopatadine hydrochloride, which is used in eye drops as antihistaminic agent, and its impurity E isomer by hydrophilic interaction liquid chromatography (HILIC) and application of design of ...
Jančić-Stojanović, Biljana   +5 more
core   +1 more source

UiO-66@Fe3O4 nanocomposite as an adsorbent in dispersive solid phase extraction of metformin in surface water and wastewater

open access: yesNano Express
Metformin, an anti-hypoglycemic medication, has been used for decades due to its efficiency and is the most consumed pharmaceutical drug worldwide. Consequently, monitoring its concentration in environmental water is important due to its suspected effect
Abigail Goitumetswe Sekopelo   +4 more
doaj   +1 more source

Actinidia arguta: Biological and Health Promoting Properties—Analysis of Bioactive Components

open access: yesPlants
Actinidia arguta, also known as mini kiwi (due to its small size) or hardy kiwi (due to its frost resistance), is becoming an increasingly popular fruit alongside its commercially older siblings, i.e., A. deliciosa (green kiwi fruit) and A.
Irena Maria Choma   +1 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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