The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Methods for structural characterisation of Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry [PDF]
This thesis describes methods for structural classification of Quillaja saponins based on high performance liquid chromatography hyphenated electrospray ionisation ion trap multiple-stage mass spectrometry, in combination with multivariate analysis ...
Bankefors, Johan
core
Esterification of rosin with methyl alcohol for fuel applications
Oleoresin is obtained via tapping of pine trees and as a by-product of Kraft process in the pulp industry. Because of its low production cost, it is an attractive source for biofuels.
Duban F. García +3 more
doaj +1 more source
Preparation and Chromatographic Analysis of Phlorotannins [PDF]
In the 70s, reports began to appear of phenolic metabolites of brown algae with the characteristics of tannins; these compounds, initially termed phaeophyte tannins, marine algal polyphenols or polyphloroglucinols, are known as phlorotannins, the youngest group of plant polyphenolics.
José Hipólito Isaza, Martínez +1 more
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Minimal number of chromatographic test parameters for the characterisation of reversed-phase liquid chromatographic stationary phases [PDF]
This paper focuses on the classification or differentiation of RP-HPLC columns based on measured chromatographic properties. A chemometric study has been conducted on a published data set consisting of 85 RP-HPLC columns and on a data set consisting of ...
T. Ivanyi +8 more
core
Sectional moving window factor analysis for diagnosing elution chromatographic patterns [PDF]
The diagnosis of elution chromatographic patterns, being a vital step in chromatographic analysis, builds fundamental ingredient for later curve resolution or fitting. Many conventional multivariate resolution methods usually hold the hypothesis that the
Zeng, Zhong Da +3 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
chromatographic fingerprinting for the detection of herbal adulteration and herbal fraud in plant food supplements [PDF]
Plant food supplements (PFS) are gaining popularity in the western world due to the general trend of returning to natural and traditional products, but also the evolution towards self-medication, the questioning of allopathic medicines and the ...
S. Ranjan, E. Deconinck
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

