Results 121 to 130 of about 4,103,456 (328)
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang+9 more
wiley +1 more source
Peak Alignment of Gas Chromatography-Mass Spectrometry Data with Deep Learning
We present ChromAlignNet, a deep learning model for alignment of peaks in Gas Chromatography-Mass Spectrometry (GC-MS) data. In GC-MS data, a compound's retention time (RT) may not stay fixed across multiple chromatograms. To use GC-MS data for biomarker
Li, Mike, Wang, X. Rosalind
core +1 more source
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett+13 more
wiley +1 more source
Japanese mandarins are becoming increasingly popular due to their pleasant aroma. The volatiles in four varieties of Japanese mandarins (Iyokan, Ponkan, Shiranui, and Unshiu mikan) were extracted by headspace solid-phase microextraction (HS-SPME) and ...
Lingyi Li+9 more
doaj +1 more source
Three field tests of a gas filter correlation radiometer [PDF]
Test flights to remotely measure nonurban carbon monoxide (CO) concentrations by gas filter correlation radiometry are discussed. The inferred CO concentrations obtained through use of the Gas Filter Correlation Radiometer (GFCR) agreed with independent ...
Campbell, S. A.+2 more
core +1 more source
Diffusion Coefficient Estimations by Thin-Channel Column Inverse Gas Chromatography : Preliminary Experiments [PDF]
A thin-channel gas chromatography column was designed and used to measure diffusion coefficients of water and iso propanol in polymer phase via inverse gas chromatography (ICC) technique.
Mohd. Nawawi, Mohd. Ghazali
core
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman+6 more
wiley +1 more source
Isotope effects in gas–liquid chromatography of steroids
When gas–liquid chromatography was performed with steroids containing H3 and C14, the H3/C14 ratio of the effluent was higher at the beginning and at the tail of the steroid peak.
Marvin A. Kirschner, Mortimer B. Lipsett
doaj
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen+16 more
wiley +1 more source