Metabolomics and Pharmacometabolomics: Advancing Precision Medicine in Drug Discovery and Development. [PDF]
Stolaki EV, Psatha K, Aivaliotis M.
europepmc +1 more source
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li +9 more
wiley +1 more source
A novel whole-greenhouse static chamber method for quantifying ecosystem respiration and nitrous oxide emissions in greenhouse cultivation systems. [PDF]
Quan Z, Li X, Zhu Y, Wei F, Fang Y.
europepmc +1 more source
A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun +12 more
wiley +1 more source
Differential Analysis of Non-Volatile and Volatile Organic Compounds in <i>Lonicerae japonicae</i> Flos Across Four Geographical Origins of China Using HS-GC-IMS, HS-SPME-GC-MS, UPLC-Q-TOF-MS, and Multivariate Statistical Methods. [PDF]
Ning X +8 more
europepmc +1 more source
Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang +3 more
wiley +1 more source
A comparative gas chromatography-mass spectrometry (GC-MS) profiling of Egyptian and Indian ashwagandha (Withania somnifera) root extracts. [PDF]
Elghazaly MM +4 more
europepmc +1 more source
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li +3 more
wiley +1 more source
Parametric study and fuel quality assessment of biofuel from hydrothermal liquefaction of microalgae grown in municipal wastewater. [PDF]
Hassan SH +6 more
europepmc +1 more source
Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao +14 more
wiley +1 more source

