Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
A View on the Synthesis and Characterization of Porous Microspheres Containing Pyrrolidone Units. [PDF]
Maciejewska M.
europepmc +1 more source
The research reveals that polysulfide anions (K2Sx), which serve as reducing catalysts, can also effectively act as sulfur reagents, providing the formation of C(sp3)─S bonds through photoredox catalysis with an oxidative photocatalyst tetrabutylammonium decatungstate (TBADT) and dual hydrogen atom transfer (DHAT) process.
Chao Zhou+8 more
wiley +1 more source
Measuring Solvation Interactions of Deep Eutectic Solvents Formed by Metal Chlorides and an Imidazolium Salt by Inverse Gas Chromatography. [PDF]
Liu S, Anderson JL.
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This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing(WGS) and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang+8 more
wiley +1 more source
Usefulness of levels of 2-methylbutyrylglycine and 2-ethylhydracrylic acid in urine for diagnosing 2-methylbutyrylglycinuria. [PDF]
Liu H+6 more
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Preparation, Structure, and Bioactivities of Medicinal and Edible Homologous Plant Polysaccharides: A Review. [PDF]
Chen M, Wei W, Wang Z, Wang W.
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Cluster Analysis of Crude Oil Genesis and Oil Source Correlation: A Case Study from the Cangdong Depression, East China. [PDF]
Lyu X+6 more
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Pyrolysis Kinetic and Radical Mechanisms of Hyperbranched Polyamidoamine, a Macroinitiator for Endothermic Hydrocarbon Fuels. [PDF]
Li S, Li S, Li Y, Dong J, He G.
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Microbiological and Geochemical Perspectives on Sustainable Dihydrogen Storage in Deep Aquifers. [PDF]
Mura J+13 more
europepmc +1 more source