Results 291 to 300 of about 1,253,208 (321)
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Thimerosal Determination by High-Pressure Liquid Chromatography
Journal of Pharmaceutical Sciences, 1978A sensitive and useful high-pressure liquid chromatographic method for the determination of intact thimerosal was developed. This method is extremely fast and reliable, and its inherent specificity makes it a breakthrough over other common wet chemical methods.
Roger Carey Meyer, Lawrence B. Cohn
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Analysis of leukotrienes by high-pressure liquid chromatography
Analytical Biochemistry, 1981Abstract A reversed-phase high-pressure liquid chromatographic procedure has been developed to separate and quantitate leukotrienes. This procedure is based on the ultraviolet absorption of the conjugated triene moiety of these compounds and is sensitive to the nanogram level.
Robert C. Murphy +2 more
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Determination of hydroxyproline by high pressure liquid chromatography
Analytical Biochemistry, 1992A rapid, precise, and simple HPLC method provides an assay of hydroxyproline from tissue extracts or solutions of collagen. Samples are hydrolyzed with 6 N HCl, derivatized with phenyl isothiocyanate, and chromatographed on a small, C18 reverse-phase HPLC column. Hydroxyproline (Hyp) is separated from other amino acids and detected by absorption at 254
Kathleen Reagan, Graham D. Green
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Anthracycline Assay by High-pressure Liquid Chromatography
Journal of Pharmaceutical Sciences, 1981A general method of analysis of anthracycline concentrations was developed. Drug is extracted from plasma with organic solvent and separated from metabolites by high-pressure liquid chromatography on an aminocyanosilica column. Detection and quantitation are by the endogenous fluorescence of compounds having an intact tetracyclic ring structure. Limits
Steven D. Averbuch +4 more
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High pressure liquid chromatography of neutral glycosphingolipids
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1972Abstract A system for the separation of neutral glycosphingolipids by high pressure liquid chromatography of their benzoylated derivatives has been devised. Serum mono-, di-, tri-and tetraglycosylceramides are completely resolved within 25 min. A full scale recorder response can be obtained with approximately 1.0 nmole of glycolipid.
James E. Evans, Robert H. McCluer
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Analysis of Trisulfapyrimidines by High-Pressure Liquid Chromatography
Journal of Pharmaceutical Sciences, 1973Abstract: The application of high-pressure liquid chromatography to the separation and analysis of trisulfapyrimidines in pharmaceutical dosage forms is demonstrated. The preparation of samples of both tablet and suspension dosage forms is simple and rapid.
Henry H. Pu, Raymond B. Poet
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Mexiletine in Plasma by High Pressure Liquid Chromatography
Therapeutic Drug Monitoring, 1981We report here a novel high pressure liquid chromatographic (HPLC) technique for use in therapeutic monitoring of the primary amine antiarrhythmic drug mexiletine in plasma samples. Mexiletine and its structural analogue, the internal standard Ko 768, are extracted with heptane after alkalinization of the sample. The extracts are evaporated to dryness,
Christmore D +4 more
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Assay of Cefotaxime by High-Pressure-Liquid Chromatography
Chemotherapy, 1981A high-pressure-liquid chromatographic (HPLC) procedure for quantitative assay of cefotaxime (CT) and its major metabolite in serum of normal individuals, desacetyl cefotaxime (DACT), is described. It employs Lichrosorb RP-8, elution with phosphoric-acid-methanol and UV absorption at 310 nm.
Tom Bergan, Rita Solberg
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Trends in High Pressure Liquid Chromatography
Berichte der Bunsengesellschaft für physikalische Chemie, 1973AbstractThe recent developments of high pressure liquid chromatography are reviewed with the emphasis on the main problems with which the users of this technic are faced: the design of more sensitive, specific detectors, the design of systems to prepare reproducible solvent gradients and to detect small concentrations of compounds in a variable ...
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High-pressure liquid chromatography of steroidal alkaloids
Journal of Chromatography A, 1976High-pressure liquid chromatography was used to separate the following steroidal alkaloids: tomatidine, solanidine, solasodine, rubijervine, veratramine and jervine. The method was used to prepare crystalline solanidine from a crude mixture of aglycones obtained from Solanum chacoense, and to separate radioactive solanidine from extracts of potato ...
Joseph R. Wagner +3 more
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