Results 51 to 60 of about 1,390,801 (312)

A chemical study of yoghurt produced under isostatic pressure during storage [PDF]

open access: yes, 2023
Yoghurt fermented under sub-lethal high pressure (10, 20, 30 and 40 MPa at 43 °C), and afterward placed under refrigeration (4 °C for 23 days) was studied and compared with yoghurt fermented at atmospheric pressure (0.1 MPa).
Delgadillo, Ivonne   +7 more
core   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Ion liquid chromatography on-a-chip with beads-packed parylene column [PDF]

open access: yes, 2004
A parylene-MEMS ion-exchange Liquid Chromatography (LC) chip is presented here. The chip is integrated with microfluidic I/O ports, a separation column, frits/filters, and a conductivity detector.
He, Qing   +3 more
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Is high pressure liquid chromatography an effective screening tool for characterization of molecular defects in hemoglobinopathies?

open access: yesIndian Journal of Pathology and Microbiology, 2013
Introduction: Hemoglobinopathies constitute entities that are generated by either abnormal hemoglobin or thalassemias. high pressure liquid chromatography (HPLC) is one of the best methods for screening and detection of various hemoglobinopathies but it ...
Nikhil Moorchung   +4 more
doaj   +1 more source

Prediction of peptide retention times in high-pressure liquid chromatography on the basis of amino acid composition.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1980
Analysis of peptides by reverse-phase high-pressure liquid chromatography would be simplified if retention times could be predicted by summing the contribution to retention of each of the peptide's amino acid side chains.
J. Meek
semanticscholar   +1 more source

Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut [PDF]

open access: yes, 1987
By hydrophobic gel permeation and high pressure liquid chromatography we isolated from pig intestinal mucosa a peptide which corresponds to proglucagon 78–107 as suggested by chromatography and determination of its N-terminal sequence.
Holst, J.J.   +3 more
core   +1 more source

Influence of telopeptides on the structural and physical properties of polymeric and monomeric acid-soluble type I collagen [PDF]

open access: yes, 2017
Currently two factors hinder the use of collagen as building block of regenerative devices: the potential antigenicity, and limited mechanical strength in aqueous environment. Polymeric collagen is naturally found in the cross-linked state and is mechanically tougher than the monomeric, cross-link-free (acid-soluble) collagen ex vivo.
arxiv   +1 more source

Adaptation of the Bridgman anvil cell to liquid pressure mediums [PDF]

open access: yesRev. Sci. Instrum. 78, 123901 (2007), 2008
The advantage of Bridgman anvil pressure cells is their wide pressure range and the large number of wires which can be introduced into the pressure chamber. In these pressure cells soft solid pressure mediums like steatite are used. We have succeeded in adapting the Bridgman cell to liquid pressure mediums.
arxiv   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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