The edoxaban‐M4 metabolite and measurement of edoxaban by chromogenic assays in human plasma
Introduction Edoxaban is the only anti‐Xa inhibitor metabolized in pharmacologically active moiety that could interfere with chromogenic anti‐Xa assays, especially in case of drug‐drug interactions or physiological disorders.
Romain Siriez+9 more
doaj +1 more source
Tropomyosin-like properties of clathrin light chains allow a rapid, high-yield purification. [PDF]
The light chains (LCa and LCb) of bovine brain clathrin are resistant to heat denaturation by boiling, a property shared by tropomyosin (Bailey, K., 1948, Biochem. J., 43:271-281).
Brodsky, FM, Holmes, NJ, Parham, P
core +2 more sources
Photodegradation Mechanisms of Tetraphenyl Butadiene Coatings for Liquid Argon Detectors [PDF]
We report on studies of degradation mechanisms of tetraphenyl butadiene (TPB) coatings of the type used in neutrino and dark matter liquid argon experiments. Using gas chromatography coupled to mass spectrometry we have detected the ultraviolet-blocking impurity benzophenone (BP).
arxiv +1 more source
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source
Complete gradient-LC-ESI system on a chip for protein analysis [PDF]
This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed ...
Lee, T. D.+3 more
core
Glycan analysis of the chicken synaptic plasma membrane glycoproteins - a major synaptic N-glycan carries the LewisX determinant [PDF]
The majority of plasma membrane components are glycosylated. It is now widely accepted that this post-translational modification is crucial during the establishment, maintenance and function of the nervous system.
Koles, Kate+3 more
core +4 more sources
Tungsten Catalysts for Visible Light Driven Ofloxacin Photocatalytic Degradation and Hydrogen Production [PDF]
Some tungsten catalysts of interest that are synthesized are bismuth tungstate (BT) and Tetrabutylammonium decatungstate (TBADT), using two consolidated procedures.
ANDREA SPELTINI+3 more
core +1 more source
Synthesis of hydrogen- and methyl-capped long-chain polyynes by intense ultrashort laser pulse irradiation of toluene [PDF]
Hydrogen- and methyl-capped polyynes were synthesized by irradiating pure liquid toluene with 35 femtosecond, 300 {\mu}J laser pulses having a central wavelength of 800 nm, generated by a regeneratively amplified Ti:sapphire tabletop laser at a repetition rate of 1 kHz.
arxiv +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Apple scab control with grapefruit seed extract: no alternative to chemical fungicides [PDF]
The growth inhibiting effect of four commercially available grapefruit seed extracts on the causal organism of apple scab Venturia inaequalis was tested.
Kelderer, Markus+5 more
core