Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Factors associated with serum concentrations of vancomycin crystalline degradation product (CDP-1) among patients with chronic kidney disease. [PDF]
BMC NephrolXu X, Yang C, Li J, Bao L, Shi Z.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng +5 more
wiley +1 more source
Analysis of Modified Plant Metabolites Using Widely Targeted Metabolite Modificomics. [PDF]
Bio ProtocZhang J +5 more
europepmc +1 more source
Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension
Advanced Healthcare Materials, EarlyView.Albumin corona alters surface properties and enhances colloidal stability by overturning pH responsiveness and nano‐aggregation behaviors of long‐acting myristic acid‐conjugated quetiapine nanosuspensions (QMN), resulting in accelerated in vitro and in vivo drug release.
Hy Dinh Nguyen +2 more
wiley +1 more source
Development of Dispersive Liquid-Liquid Microextraction Method Based on Solidification of Floating Organic Droplets for Rapid Determination of Three Strigolactones in Rice (<i>Oryza sativa</i> L.) Using Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry. [PDF]
Int J Mol SciZhu X +5 more
europepmc +1 more source
Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Advanced Materials, EarlyView.Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach +4 more
wiley +1 more source
Electrospray-Mass Spectrometry-Guided Targeted Isolation of Indole Alkaloids from Leaves of <i>Catharanthus roseus</i> by Using High-Performance Countercurrent Chromatography. [PDF]
MoleculesYahyazadeh M, Selmar D, Jerz G.
europepmc +1 more source
Conductive Polymer Coatings Control Reaction Selectivity in All‐Iron Redox Flow Batteries
Advanced Materials, EarlyView.Aqueous redox flow batteries are limited by the competing hydrogen evolution reaction (HER) at their negative electrodes. In this work, conductive polymers are conformally coated on porous carbonaceous electrodes to improve the reaction selectivity of hybrid all‐iron redox flow batteries.
Emre B. Boz +3 more
wiley +1 more source