Results 181 to 190 of about 10,732 (222)
Some of the next articles are maybe not open access.
Chromenes as Anticancer Agents
2023Heterocyclic compounds hold an important place in the realm of medicinal chemistry due to their vast pharmacological and therapeutic significance. Worldwide, cancer is the leading cause of death, and developing an appropriate treatment for the management of cancer is a challenge.
Parul Grover +3 more
openaire +1 more source
Isomerization of phenolic chromens
Journal of the Chemical Society, Chemical Communications, 1976Direct evidence of thermal, acid, and base catalysed isomerization of phenolic 2,2-dialkylchromens has been obtained with the monochromens formed from 2,4-dihydroxyacetophenone.
Gary D. Manners, Leonard Jurd
openaire +1 more source
Leishmanicidal Evaluation of Novel Synthetic Chromenes
Archiv der Pharmazie, 2008AbstractIn the present paper, twelve chromenes were synthesized by coupling of 2,2,8,8‐tetramethyl‐8H‐pyrano[2,3‐f]chroman‐4‐one 1 with various aryl and benzylmagnesium chlorides. The synthetic compounds were examined for in‐vitro activity against Leishmania major, and some of them displayed efficient anti‐leishmanial activity.
Babak Heidary, Alizadeh +4 more
openaire +2 more sources
Chromenes from Ageratina arsenii and revised structures of two epimeric chromene dimers
Phytochemistry, 1988Abstract Agrostophyllin, the first naturally occurring phenanthropyran derivative, was isolated from the orchid Agrostophyllum khasiyanum .
Nianbai Fang, Sanggong Yu, Tom J. Mabry
openaire +1 more source
Biological importance of structurally diversified chromenes
European Journal of Medicinal Chemistry, 2016Compounds incorporating the chromene scaffold are largely present in natural products and display a wide variety of biological activities. Their low toxicity combined to the broad pharmacological properties have inspired medicinal chemists in the search for new therapeutic agents.
Costa, M. +3 more
openaire +3 more sources
New 4H-chromen-4-one and 2H-chromene derivatives as anti-picornavirus capsid-binders
Bioorganic & Medicinal Chemistry, 2010Substituted (E)-3-styryl-4H-chromen-4-ones 1a-d, 3-[(1E,3E)-4-phenylbuta-1,3-dienyl]-4H-chromen-4-ones 2a-d, (E)-3-styryl-2H-chromenes 3a-d and 3-[(1E,3E)-4-phenylbuta-1,3-dienyl]-2H-chromenes 4a-d were designed and synthesized to improve the anti-picornavirus activity of previously tested analogues.
CONTI, Cinzia, DESIDERI, Nicoletta
openaire +3 more sources
Novel chromene derivatives as TNF-α inhibitors
Bioorganic & Medicinal Chemistry Letters, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Jie-Fei, Cheng +4 more
openaire +2 more sources
J. Chem. Soc., Chem. Commun., 1976
The chromens (2) and (3), at 110 °C in pyridine, are converted into citrans by a hitherto unexpected rearrangement involving thermal electrocyclic opeing, (E)/(Z) isomerisation and tautomerism of the intermediate dienones, and reclosure to the alternative chromens; citran formation then proceeds from either of the equilibrating chromens.
Leslie Crombie +2 more
openaire +1 more source
The chromens (2) and (3), at 110 °C in pyridine, are converted into citrans by a hitherto unexpected rearrangement involving thermal electrocyclic opeing, (E)/(Z) isomerisation and tautomerism of the intermediate dienones, and reclosure to the alternative chromens; citran formation then proceeds from either of the equilibrating chromens.
Leslie Crombie +2 more
openaire +1 more source
The synthesis of 5-hydroxy chromenes
Canadian Journal of Chemistry, 1985The synthesis of 2,2-dimethyl-5-hydroxychromene (1d) is described. The synthesis of the analogous 5,7-dihydroxy derivatives, using similar conditions, yields the adduct 9 derived via a Bucherer type reaction. X-ray analysis of 9 demonstrated that a pyrrolidine group was in the 7-position, and that the 5-hydroxyl group was involved in a strong ...
J. W. ApSimon, L. W. Herman, C. Huber
openaire +1 more source
A fungistatic chromene fromAgeratum conyzoides
Phytoparasitica, 2004Ageratum conyzoides L. is an annual herb in the tropics and subtropics whose extracts are known to possess pharmacological and biocidal activity. We report on the bioactivity of a secondary metabolite (a chromene) isolated from the shoots ofA. conyzoides against some plant pathogenic fungi.
M. C. M. Iqbal +4 more
openaire +1 more source