Results 61 to 70 of about 241,523 (262)

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo   +12 more
wiley   +1 more source

Smart alloys for a future fusion power plant: First studies under stationary plasma load and in accidental conditions

Nuclear Materials and Energy, 2017
In case of an accident in the future fusion power plant like DEMO, the loss-of-coolant may happen simultaneously with air ingress into the vacuum vessel. The radioactive tungsten and its isotopes from the first wall may become oxidized and vaporized into
A. Litnovsky, T. Wegener, F. Klein, Ch. Linsmeier, M. Rasinski, A. Kreter, B. Unterberg, M. Vogel, S. Kraus, U. Breuer, C. Garcia-Rosales, A. Calvo, N. Ordas   +12 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

XAFS spectrum of Chromium

This dataset consists of X-ray absorption fine structure (XAFS) spectra at Cr K-edge of Chromium measured at PF, and is a part of XAFS database (MDR XAFS DB, https://doi.org/10.48505/nims.1447) as a collection of ...
Kiyotaka Asakura
core   +2 more sources

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

Advanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu, Yufei Zhang, Han Zhao, Pooi See Lee, Daniel H.C. Chua   +4 more
wiley   +1 more source

The role of soil components in synthetic mixtures during the adsorption and speciation changes of Cr(VI): Conjunction of the modeling approach with spectroscopic and isotopic investigations

Environment International, 2019
This study investigates redox transitions associated with the adsorption of Cr(VI) on commonly occurring soil components (silicates, oxides and humic acids) and their synthetic mixtures by coupling the mechanistic surface complexation modeling with ...
Veronika Veselská, Hana Šillerová, Jörg Göttlicher, Zuzana Michálková, Jamal A. Siddique, Sylva Číhalová, Vladislav Chrastný, Ralph Steininger, Stefan Mangold, Michael Komárek   +9 more
doaj   +1 more source

Synthesis and characterisation of chromium (III) complexes with polypyridyl ligands [PDF]

, 2014
Slowing down climate change is probably the biggest current global challenge for mankind. The two main strategies to achieve this are the development of new sustainable energy sources and new or improved technologies that are less energy consuming ...
Schönle, Jonas Michael
core   +1 more source

Quasidynamical symmetries in the backbending of chromium isotopes

Physical Review C, 2017
23 pages, 16 figures; modified after referee and editorial ...
Herrera, Raul A., Johnson, Calvin W.
openaire   +3 more sources

Diffusion of Hydrogen Isotopes in Zirconium Alloys

He huaxue yu fangshe huaxue
Tritium is a common radioactive product in nuclear power plants. It is easy to diffuse, penetrate and be easily absorbed by organisms due to its small atomic radius.
Long WANG, Zhi-hao HONG, You-zhi WANG, Zi-kai LIU, Xiao-qian ZHANG, Tian-guang ZHANG, Long ZHANG   +6 more
doaj   +1 more source

Neutron capture by the chromium isotopes.

, 1977
Capture cross sections of the chromium isotopes have been measured at neutron energies up to 350 keV using the capture cross section facility at the 40 m station of the Oak Ridge Electron Linear Accelerator.
Macklin, RL, Kenny, MJ, Musgrove, ARD, Halperin, J, Allen, BJ   +4 more
core