Results 21 to 30 of about 3,673 (128)
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Transcriptional Assessment by Microarray Analysis and Large-Scale Meta-analysis of the Metabolic Capacity of Cardiac and Skeletal Muscle Tissues to Cope With Reduced Nutrient Availability in Gilthead Sea Bream (Sparus aurata L.) [PDF]
, 2017 The effects of nutrient availability on the transcriptome of cardiac and skeletal muscle tissues were assessed in juvenile gilthead sea bream fed with a standard diet at two feeding levels: (1) full ration size and (2) 70 % satiation followed by a ...
Baron, Daniel +6 more
core +1 more source
ATRX: From Chromatin Remodeling to Disease
genesis, Volume 63, Issue 6, December 2025.ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta +1 more
wiley +1 more source
Systemic similarity analysis of compatibility drug-induced multiple pathway patterns _in vivo_ [PDF]
, 2008 A major challenge in post-genomic research is to understand how physiological and pathological phenotypes arise from the networks of expressed genes and to develop powerful tools for translating the information exchanged between gene and the organ system
Weida Tong +5 more
core +1 more source
Journal of Diabetes, Volume 17, Issue 12, December 2025.The levels of DKK1 in patients with PCOS and IR are significantly elevated, revealing a potential relationship between DKK1, PCOS, and metabolic disorders, and suggesting that DKK1 may serve as a biomarker associated with PCOS and metabolic disorders.
Jiaxiu Ling +9 more
wiley +1 more source
Generalized Monotone Incremental Forward Stagewise Method for Modeling Count Data: Application Predicting Micronuclei Frequency [PDF]
, 2015 The cytokinesis-block micronucleus (CBMN) assay can be used to quantify micronucleus (MN) formation, the outcome measured being MN frequency. MN frequency has been shown to be both an accurate measure of chromosomal instability/DNA damage and a risk ...
Archer, Kellie J., Makowski, Mateusz
core +2 more sources
Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island [PDF]
, 2007 Background: A sensitive, ubiquitously expressed tetracycline inducible system would be a valuable tool in mouse transgenesis. However, this has been difficult to obtain due to position effects observed at different chromosomal sites of transgene ...
Eleni Z Katsantoni +7 more
core +5 more sources
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Cancer Communications, Volume 45, Issue 9, Page 1128-1161, September 2025.Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu +7 more
wiley +1 more source
Decreased brain-expressed X-linked 4 (BEX4) expression promotes growth of oral squamous cell carcinoma [PDF]
, 2016 © 2016 Gao et al.Background: Brain-expressed X-linked (BEX) 4 is a member of BEX family. The functional role of BEX4 in oral squamous cell carcinoma (OSCC) remains unknown.
Chan, Jimmy Yu Wai +5 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 41, Issue 9, September 2025.ABSTRACT S100 calcium‐binding protein A7 (S100A7) has been implicated in psoriasis and other inflammatory diseases. However, the function of S100A7 in oral lichen planus (OLP), a chronic inflammatory disease, remains unclear. OLP was induced in mice by transplanting human OLP lesions into the backs of thymus‐free mice, and an in vitro cell model was ...
Maimaiti Tudi +3 more
wiley +1 more source