A DNN Biophysics Model with Topological and Electrostatic Features [PDF]
In this project, we provide a deep-learning neural network (DNN) based biophysics model to predict protein properties. The model uses multi-scale and uniform topological and electrostatic features generated with protein structural information and force field, which governs the molecular mechanics.
arxiv
Protriever: End-to-End Differentiable Protein Homology Search for Fitness Prediction [PDF]
Retrieving homologous protein sequences is essential for a broad range of protein modeling tasks such as fitness prediction, protein design, structure modeling, and protein-protein interactions. Traditional workflows have relied on a two-step process: first retrieving homologs via Multiple Sequence Alignments (MSA), then training models on one or more ...
arxiv
Q. Xiao+8 more
semanticscholar +1 more source
RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination. [PDF]
Zhao Q, Liu N, Xu T, Song K.
europepmc +1 more source
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer. [PDF]
Yang H, Pu L, Li R, Zhu R.
europepmc +1 more source
Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects. [PDF]
da Trindade NS+7 more
europepmc +1 more source
Transposable element dynamics in Xenopus laevis embryogenesis: a tale of two coexisting subgenomes. [PDF]
Tittarelli E+5 more
europepmc +1 more source
Integrated bioinformatics investigation and experimental validation reveals the clinical and biological significance of chromobox family in breast cancer. [PDF]
Ge X+7 more
europepmc +1 more source
The arms race of ray-finned fish against the derepression of LTR retroelements. [PDF]
Carotti E+5 more
europepmc +1 more source
An African swine fever virus Bc1-2 homolog, 5-HL, suppresses apoptotic cell death
C. Afonso, J. Neilan, G. Kutish, D. Rock
semanticscholar +1 more source