Results 91 to 100 of about 39,459 (267)

Characterization of hormone and protein release from alpha-toxin- permeabilized chromaffin cells in primary culture [PDF]

open access: yes, 1986
Addition of Staphylococcus aureus alpha-toxin to adult bovine chromaffin cells maintained in primary culture causes permeabilization of cell membrane as shown by the release of intracellular 86Rb+.
Ahnert-Hilger, G.   +4 more
core  

Untersuchungen zur transkriptionellen Regulation des Chromogranin A Gens und seine Anwendung zum zellspezifischen therapeutischen Gentransfer in neuroendokrine Pankreastumorzellen [PDF]

open access: yes, 2003
Die Therapieoptionen zur Behandlung metastasierter neuroendokriner Tumore sind bisher ineffektiv. Der regulierte Gentransfer könnte eine weitere Möglichkeit eröffnen, metastasierte neuroendokrine Tumore zu behandeln.
Bert, Tillmann, Simon, B. (PD Dr. med)
core   +1 more source

The role of peripheral serotonin in SARS‐CoV‐2 infectivity, COVID‐19 treatment and long COVID

open access: yesImmunology &Cell Biology, EarlyView.
In this article, we discuss how SARS‐CoV‐2 infects the gastrointestinal tract, that enterochromaffin cells, the source of circulating serotonin, uniquely express viral entry receptors. We examine how this infection disrupts gut‐derived serotonin, contributing to gastrointestinal symptoms and disease severity, and link elevated plasma serotonin to COVID‐
Daniel W Thorpe   +6 more
wiley   +1 more source

Diagnostic value of plasma chromogranin A levels for pheochromocytoma

open access: yesZhongguo linchuang yanjiu
Objective To investigate the role of plasma chromogranin A (CgA) and free metanephrines (MNs) levels in the diagnosis of pheochromocytoma (PHEO). Methods The clinical data of 26 patients with PHEO (PHEO group) and 31 patients with other adrenal ...
CUI Hao, QIN Wuyao, WANG Jinyao, SHANG Jiwen
doaj   +1 more source

Chromogranin A: As A Tumor Marker for Neuroendocrine Tumors Diagnosis, Follow-up & Its Correlation with Response to Somatostatin Analogues

open access: yesمجلة كلية الطب, 2016
Background: Chromogranin A is a useful tumor marker for neuroendocrine tumors (NETs) diagnosis & follow-up, Octreotide (somatostatin-long acting repeatable (SAS-LAR)) is an established treatment for NETs.
Manwar A. Mohammed AL-Naqqash
doaj   +1 more source

Potential novel therapy targets in neuroendocrine carcinomas of the breast [PDF]

open access: yes, 2018
Neuroendocrine carcinoma (NEC) of the breast is a rare, special type of breast cancer, reportedly constituting 2% to 5% of all breast cancers. Although breast NEC does not have a specific targeted therapy, several new targeted therapies based on specific
Contreras, Elma   +7 more
core   +2 more sources

Endoscopic Ultrasound for the Management of Pancreatic Neuroendocrine Tumors: Diagnosis, Treatment, and Future Perspectives

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Pancreatic neuroendocrine tumors (PanNETs) are increasingly diagnosed, reflecting greater clinical awareness, improved imaging, and revised classification. This review summarizes evidence on epidemiology, diagnostic workup, and endoscopic ultrasound (EUS)–guided management of PanNETs, encompassing diagnostic evaluation, tissue acquisition, and
Angelo Bruni   +7 more
wiley   +1 more source

Glucagon and insulin immunopositivity of mast cells in porcine gallbladder

open access: yesBulgarian Journal of Veterinary Medicine
It is well known that mast cells produce and release biologically active substances such as histamine, heparin, proteases, leukotrienes, cytokines, chemokines and growth factors. According to the avail-able scientific literature on that topic this is the
I. Stefanov, S. Stefanov, M. Gulubova
doaj   +1 more source

Pitfalls in the diagnosis of carcinoid syndrome

open access: yesFamily Medicine & Primary Care Review, 2016
Background . Carcinoid syndrome (CS ) is a rare syndrome, most commonly associated with neuroendocrine neoplasms (NEN s) of the small intestine. Carcinoid syndrome consists of diarrhea, vomiting, abdominal pain, cutaneous flushing, teleangiectasias ...
Dorota Kaczmarska-Turek   +8 more
doaj   +1 more source

Chromogranin A in the pancreatic islet [PDF]

open access: yes, 1986
Chromogranin A (CGA) is the major soluble protein within secretory vesicles of chromaffin cells. A polyclonal antiserum was raised against bovine CGA and characterized in two-dimensional immunoblots. Cellular and subcellular distribution of CGA in bovine
Aunis, D.   +4 more
core  

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