Results 91 to 100 of about 39,459 (267)
Characterization of hormone and protein release from alpha-toxin- permeabilized chromaffin cells in primary culture [PDF]
Addition of Staphylococcus aureus alpha-toxin to adult bovine chromaffin cells maintained in primary culture causes permeabilization of cell membrane as shown by the release of intracellular 86Rb+.
Ahnert-Hilger, G. +4 more
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Untersuchungen zur transkriptionellen Regulation des Chromogranin A Gens und seine Anwendung zum zellspezifischen therapeutischen Gentransfer in neuroendokrine Pankreastumorzellen [PDF]
Die Therapieoptionen zur Behandlung metastasierter neuroendokriner Tumore sind bisher ineffektiv. Der regulierte Gentransfer könnte eine weitere Möglichkeit eröffnen, metastasierte neuroendokrine Tumore zu behandeln.
Bert, Tillmann, Simon, B. (PD Dr. med)
core +1 more source
The role of peripheral serotonin in SARS‐CoV‐2 infectivity, COVID‐19 treatment and long COVID
In this article, we discuss how SARS‐CoV‐2 infects the gastrointestinal tract, that enterochromaffin cells, the source of circulating serotonin, uniquely express viral entry receptors. We examine how this infection disrupts gut‐derived serotonin, contributing to gastrointestinal symptoms and disease severity, and link elevated plasma serotonin to COVID‐
Daniel W Thorpe +6 more
wiley +1 more source
Diagnostic value of plasma chromogranin A levels for pheochromocytoma
Objective To investigate the role of plasma chromogranin A (CgA) and free metanephrines (MNs) levels in the diagnosis of pheochromocytoma (PHEO). Methods The clinical data of 26 patients with PHEO (PHEO group) and 31 patients with other adrenal ...
CUI Hao, QIN Wuyao, WANG Jinyao, SHANG Jiwen
doaj +1 more source
Background: Chromogranin A is a useful tumor marker for neuroendocrine tumors (NETs) diagnosis & follow-up, Octreotide (somatostatin-long acting repeatable (SAS-LAR)) is an established treatment for NETs.
Manwar A. Mohammed AL-Naqqash
doaj +1 more source
Potential novel therapy targets in neuroendocrine carcinomas of the breast [PDF]
Neuroendocrine carcinoma (NEC) of the breast is a rare, special type of breast cancer, reportedly constituting 2% to 5% of all breast cancers. Although breast NEC does not have a specific targeted therapy, several new targeted therapies based on specific
Contreras, Elma +7 more
core +2 more sources
ABSTRACT Pancreatic neuroendocrine tumors (PanNETs) are increasingly diagnosed, reflecting greater clinical awareness, improved imaging, and revised classification. This review summarizes evidence on epidemiology, diagnostic workup, and endoscopic ultrasound (EUS)–guided management of PanNETs, encompassing diagnostic evaluation, tissue acquisition, and
Angelo Bruni +7 more
wiley +1 more source
Glucagon and insulin immunopositivity of mast cells in porcine gallbladder
It is well known that mast cells produce and release biologically active substances such as histamine, heparin, proteases, leukotrienes, cytokines, chemokines and growth factors. According to the avail-able scientific literature on that topic this is the
I. Stefanov, S. Stefanov, M. Gulubova
doaj +1 more source
Pitfalls in the diagnosis of carcinoid syndrome
Background . Carcinoid syndrome (CS ) is a rare syndrome, most commonly associated with neuroendocrine neoplasms (NEN s) of the small intestine. Carcinoid syndrome consists of diarrhea, vomiting, abdominal pain, cutaneous flushing, teleangiectasias ...
Dorota Kaczmarska-Turek +8 more
doaj +1 more source
Chromogranin A in the pancreatic islet [PDF]
Chromogranin A (CGA) is the major soluble protein within secretory vesicles of chromaffin cells. A polyclonal antiserum was raised against bovine CGA and characterized in two-dimensional immunoblots. Cellular and subcellular distribution of CGA in bovine
Aunis, D. +4 more
core

