Results 41 to 50 of about 39,459 (267)
Advanced Healthcare Materials, EarlyView.To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
Primary breast neuroendocrine carcinoma: a case report and literature review
Zhongguo linchuang yanjiuObjective To report a case of primary neuroendocrine breast cancer (NEBC)，and to provide clinical reference for the diagnosis and treatment of the disease.
CHEN Jiaying +3 more
doaj +1 more source
bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice [PDF]
, 2015 Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibility
Abuderman, A A +5 more
core +2 more sources
Advanced Science, EarlyView.Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu +12 more
wiley +1 more source
Is there any neuroendocrine differentiation in squamous cell carcinoma of larynx?
Turkish Archives of Otorhinolaryngology, 2010 Objectives: To investigate the expressions of distinct neuroendocrine (NE) markers in larynx cancer to find out possible prognostic implications.Methods: Thirty patients were evaluated in this prospective study. Tumors were graded according to the degree
M. Kürşat Gökcan +2 more
doaj +1 more source
Effects of Ostertagia circumcincta larvae and adult parasites on abomasal and intestinal tissues in sheep : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology [PDF]
, 1994 Ostertagia circumcincta parasites infect the abomasum of sheep causing damage to the abomasal tissues and significant production losses to the sheep farming industry.
Hodgkinson, Suzanne Marie
core
Malignancy within a tail gut cyst:a case of retrorectal carcinoid tumour [PDF]
, 2014 Purpose. Tailgut cysts with malignant transformation are rare entities. We discuss the diagnostic strategy and treatment of a malignancy within a tailgut cyst. Methods.
Abukar, A. A. +7 more
core +7 more sources
Advanced NanoBiomed Research, EarlyView.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Ca2+ binding to Chromaffin Vesicle Matrix Proteins [PDF]
, 1986 Recently we found that Ca2+ within chromaffin vesicles is largely bound [Bulenda, D., & Gratzl, M. (1985) Biochemistry 24, 7760-77651. In order to explore the nature of these bonds, we analyzed the binding of Ca2+ to the vesicle matrix proteins as well ...
Gratzl, Manfred, Reiffen, F. U.
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objectives Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biological mechanism underlying this association. Methods Expression of surrounding genes was compared between rs26232 genotypes.
Kevin J. Sheridan +12 more
wiley +1 more source