Results 61 to 70 of about 39,459 (267)

Cytomorphology and Molecular Profile of Hyalinizing Clear Cell Carcinoma of the Lung: A Case With Mucinous Differentiation

Diagnostic Cytopathology, EarlyView.
ABSTRACT Hyalinizing clear cell carcinoma (HCCC) of the lung is an exceedingly rare salivary gland‐type neoplasm with limited cytomorphologic description. We report a case highlighting these features. A 3 mm incidental left‐airway lesion enlarged to 7 mm over 5 months, prompting radial endobronchial ultrasound (EBUS)‐guided transbronchial biopsy. Touch
Jeffrey Zijie Lin, Lucy Jager
wiley   +1 more source

FEATURES OF CHRONIC PANCREATITIS PATHOMORPHISM IN THE VALIDITY OF SURGICAL APPROACHES

Вестник хирургии имени И.И. Грекова, 2018
The results of examination and surgical treatment of 298 patients with chronic pancreatitis and the original morphological investigations of material of the pancreas were studied.
N. A. Maistrenko, Ye. I. Chumasov, Ye. S. Petrova, V. S. Dovganyuk, P. N. Romashchenko, A. S. Pryadko, I. Yu. Boiko, D. E. Korzhevsky   +7 more
doaj   +1 more source

May Salivary Chromogranin A Act as a Physiological Index of Stress in Transported Donkeys? A Pilot Study

Animals, 2020
Road transport is known to be a stressful animal husbandry procedure as it induces the activation of two main physiological stress-related pathways: the hypothalamic-pituitary-adrenal cortex axis and the sympathetic-adrenal medulla axis. This preliminary
Francesca Dai, Emanuela Dalla Costa, Simona Cannas, Eugenio Ugo Luigi Heinzl, Michela Minero, Silvia Michela Mazzola   +5 more
doaj   +1 more source

Chromogranin A and its fragments as regulators of small intestinal neuroendocrine neoplasm proliferation. [PDF]

PLoS ONE, 2013
Chromogranin A is a neuroendocrine secretory product and its loss is a feature of malignant NEN de-differentiation. We hypothesized that chromogranin A fragments were differentially expressed during NEN metastasis and played a role in the regulation of ...
Francesco Giovinazzo, Simon Schimmack, Bernhard Svejda, Daniele Alaimo, Roswitha Pfragner, Irvin Modlin, Mark Kidd   +6 more
doaj   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, EarlyView.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

CLINICAL VALUE OF CHROMOGRANIN A IN GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Neuroendocrine tumors (NET) is a heterogeneous group of neoplasms characterized by hypersecretion of biologically active sub- stances that manifests by specific syndromes and determines the clinical course of the disease.
N. V. Lyubimova, M. G. Toms, T. K. Churikova, T. Yu. Kharitid   +3 more
doaj   +1 more source

Chromogranin a Measurement in Neuroendocrine Tumors

The International Journal of Biological Markers, 1998
Neuroendocrine tumors (NETs) are rare neoplasms characterized by a low proliferative index and, in some cases, a favorable prognosis. These tumors often overproduce and release biologically active substances that are responsible for severe syndromes.
L, Ferrari, E, Seregni, A, Martinetti, B, Van Graafeiland, S, Nerini-Molteni, C, Botti, S, Artale, S, Cresta, E, Bombardieri   +8 more
openaire   +2 more sources

Calcium‐dependence of chromogranin A‐catecholamine interaction [PDF]

FEBS Letters, 1988
Major components of the secretory organelle of bovine adrenal medullary cells, the chromaffin vesicles, are the acidic protein chromogranin A, catecholamines and Ca2+. The binding of Ca2+ to chromogranin A has been established. To study the interaction between chromogranin A and catecholamines and its dependence on Ca2+ we immobilized chromogranin A to
Westermann, R., Stögbauer, F., Unsicker, K., Lietzke, R.   +3 more
openaire   +2 more sources

Molecular–clinical characteristics and treatment outcomes in 163 metastatic colorectal neuroendocrine carcinomas with a comparison to colorectal adenocarcinomas

International Journal of Cancer, EarlyView.
What's New? Colorectal neuroendocrine carcinoma (CR‐NEC) is a rare digestive neuroendocrine neoplasm that frequently exhibits an adenocarcinoma component. Nonetheless, the underlying biology of CR‐NEC remains poorly understood. This study examined molecular and clinical features and palliative chemotherapy outcomes of metastatic CR‐NEC, with comparison
Siren Morken, Seppo W. Langer, Geir Olav Hjortland, Anna Sundlöv, Eva Hofsli, Morten Ladekarl, Elizaveta Tabaksblat, Lene Weber Vestermark, Johanna Svensson, Ulrich Knigge, Luís Nunes, Bengt Glimelius, Per Pfeiffer, Kristine Aasebø, Jörg Assmus, Erik Vassella, Inger Marie Bowitz Lothe, Anne Couvelard, Aurel Perren, Stian Knappskog, Halfdan Sorbye   +20 more
wiley   +1 more source

Lower serum chromogranin B level is associated with type 1 diabetes and with type 2 diabetes patients with intensive conservative insulin treatment

Diabetology & Metabolic Syndrome, 2020
Background Chromogranin B (CgB) plays an important role in the physiological insulin secretion of pancreatic beta cells. Serum CgB levels were investigated in type 1 and type 2 diabetes patients in a cross-sectional study.
Zoltan Herold, Magdolna Herold, Klara Rosta, Marton Doleschall, Aniko Somogyi   +4 more
doaj   +1 more source