Results 111 to 120 of about 222,747 (199)

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Study of Chromosomal Abnormalities in Couples with Recurrent Spontaneous Abortions (RSA) in Ardabil Province

Journal of Ardabil University of Medical Sciences, 2018
Background & objectives: The spontaneous abortion, loss of the fetus until the twentieth week of pregnancy, is one of the most common medical problems in reproductive age.
Ziba Jahani, Seyyed saeid Hosseini Asl, Homa Akhavan   +2 more
doaj  

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia [PDF]

, 2004
Heidi E. Lilja, Elina Suviolahti, Aino Soro‐Paavonen, Tero Hiekkalinna, Aaron J. Day, Kenneth Lange, Eric M. Sobel, Marja‐Riitta Taskinen, Leena Peltonen, Markus Perola, Päivi Pajukanta   +10 more
openalex   +1 more source

Y‐chromosomal red‐green opsin genes of nocturnal New World monkey¹ [PDF]

, 2002
Shoji Kawamura, Naomi Takenaka, Chihiro Hiramatsu, Momoki Hirai, Osamu Takenaka   +4 more
openalex   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, EarlyView.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

, 2016
Josée Guirouilh‐Barbat, Camille Gelot, Anyong Xie, Elodie Dardillac, Ralph Scully, Bernard S. López   +5 more
openalex   +2 more sources

Forensic parameters and genetic structure based on Y-chromosome short tandem repeats in Lesotho populations [PDF]

, 2019
Mpasi Lesaoana, Mohaimin Kasu, María Eugenia D’Amato   +2 more
openalex   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source