Results 151 to 160 of about 1,728,680 (388)

A cytogenetic study of couples with repeated spontaneous abortions

Annals of Saudi Medicine, 2011
Background and Objective : The frequency of chromosomal aberrations in Iran is not definitely known. This study determined the frequency of chromosomal aberrations in a series of couples with two or more spontaneous abortions and compared the findings ...
Niroumanesh Shirin, Mehdipour Parvin, Farajpour Ali, Darvish Soodabeh   +3 more
doaj  

\u3cem\u3eRhizobium phaseoli\u3c/em\u3e Symbiotic Mutants with Transposon Tn5 Insertions [PDF]

, 1984
Rhizobium phaseoli CFN42 DNA was mutated by random insertion of Tn5 from suicide plasmid pJB4JI to obtain independently arising strains that were defective in symbiosis with Phaseolus vulgaris but grew normally outside the plant.
Cevallos, Miguel A., Fernandez, Leonor, Leemans, Jan, Noel, K. Dale, Sanchez, Araceli   +4 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Retrospective study revealed integration of CNV-seq and karyotype analysis is an effective strategy for prenatal diagnosis of chromosomal abnormalities

Frontiers in Genetics
Fetal chromosomal abnormalities are the main cause of adverse pregnancy outcomes and are the focus of invasive prenatal diagnosis. Recent studies have demonstrated that various techniques have distinct advantages.
Yunsheng Ge, Jiayan Chen, Yanru Huang, Di Shao, Wenbo Wang, Meijiao Cai, Meihua Tan, Meihua Tan, Jian Zhang   +8 more
doaj   +1 more source

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.

Proceedings of the National Academy of Sciences of the United States of America, 2000
K. Datsenko, B. Wanner
semanticscholar   +1 more source

Whole genome sequence analysis reveals genetic structure and X-chromosome haplotype structure in indigenous Chinese pigs [PDF]

, 2020
Xiong Tong, Lianjie Hou, Weiming He, Chugang Mei, Bo Huang, Chi Zhang, Ching Yuan Hu, Chong Wang   +7 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

A comparative genomic analysis at the chromosomal-level reveals evolutionary patterns of aphid chromosomes

Communications Biology
Genomic rearrangements are primary drivers of evolution, promoting biodiversity. Aphids, an agricultural pest with high species diversity, exhibit rapid chromosomal evolution and diverse karyotypes.
Chen Huang, Bingru Ji, Zhaohui Shi, Jiangyue Wang, Jiaqing Yuan, Peng Yang, Xiao Xu, Haohao Jing, Lulu Xu, Jing Fu, Le Zhao, Yandong Ren, Kun Guo, Gang Li   +13 more
doaj   +1 more source

Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia

, 2023
Vanessa M. Conn, Marta Gabryelska, John Toubia, Kirsty Kirk, Laura Gantley, Jason A. Powell, Gökhan Cildir, Shashikanth Marri, Ryan Liu, Brett W. Stringer, Scott L. Townley, Stuart T. Webb, Lin He, Saumya E. Samaraweera, Sheree Bailey, Andrew S. Moore, Mellissa Maybury, Dawei Liu, Alex D. Colella, Tim Chataway, Craig T. Wallington‐Beddoe, Lucie Walters, Jane Sibbons, Luke A. Selth, Vinay Tergaonkar, Richard J. D’Andrea, Stuart M. Pitson, Gregory J. Goodall, Simon J. Conn   +28 more
openalex   +2 more sources